| Categories genes  | Tags mitochondria  map-based cloning  cell death  PCD  lesion  lesion mimic 
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    • Furthermore, confocal microscopy showed that the E409V mutation impairs localization of OsDRP1E to the mitochondria
    • We used a map-based cloning strategy to isolate OsDRP1E from the lesion mimic mutant dj-lm and confirmed that the E409V mutation in OsDRP1E causes spontaneous cell death in rice
    • The Rice Dynamin-Related Protein OsDRP1E Negatively Regulates Programmed Cell Death by Controlling the Release of Cytochrome c from Mitochondria.
    • Taken together, our results demonstrate that the mitochondria-localized protein OsDRP1E functions as a negative regulator of cytochrome c release and PCD in plants
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