WFSL1,STRIPE3

• Symbol: WFSL1,STRIPE3
• MSU: LOC_Os01g01920
• RAPdb: Os01g0109300

• Single-point Mutation of an Histidine-aspartic Domain-containing Gene involving in Chloroplast Ribosome Biogenesis Leads to White Fine Stripe Leaf in Rice., 2017, Sci Rep.
• STRIPE3, encoding a human dNTPase SAMHD1 homolog, regulates chloroplast development in rice., 2022, Plant Sci.

Genbank accession number

• The wfsl1 displayed white fine stripe leaves since tillering stage and abnormal chloroplast structure
• RNA-seq analysis revealed that chloroplast development and photosynthesis genes were significantly affected in wfsl1 plants
• Levels of WFSL1 and chloroplast encoded proteins were decreased in wfsl1 mutants via western blot analysis
• Compared with WT, wfsl1 exhibits lower Chl content and defective in biogenesis of chloroplast ribosomes, which resulted in reduced grain yield
• Taken together, our results show that WFSL1 is critical for chloroplast development, ribosome biogenesis, and light energy utilization, finally affects grain yield
• Map-based cloning and Bioinformatic analysis indicated that WFSL1 on chromosome 1 contains an "A" to "T" substitution in protein coding region, and encodes a putative metal-dependent phosphohydrolase with HD domain at the N-terminus
• Here, we isolated and characterized the stripe3 (st3) mutant which exhibited white-striped leaves with reduced chlorophyll content and abnormal chloroplast development during the seedling stage, but gradually produced nearly normal green leaves as it developed