- Information
- Symbol: OsATM
- MSU: LOC_Os01g01689
- RAPdb: Os01g0106700,Os01g0106750
- Publication
- OsATM safeguards accurate repair of meiotic double-strand breaks in rice., 2020, Plant Physiol.
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Genbank accession number
- Key message
- Aberrant chromosome associations and DNA fragmentations were observed after the completion of homologous pairing and synapsis in Osatm pollen mother cells (PMCs)
- OsATM safeguards accurate repair of meiotic double-strand breaks in rice.
- Together, these findings suggest that OsATM plays important roles in the accurate repair of meiotic DSBs in rice
- Aberrant chromosome associations disappeared in Osspo11-1 Osatm-1 double mutants and more severe defects were observed in Osdmc1 Osatm, suggesting that OsATM functions downstream of OsSPO11-1-catalyzed double-strand break (DSB) formation and in parallel with OsDMC1-mediated homologous recombination
- Connection
- H2AX, OsATM, OsATM safeguards accurate repair of meiotic double-strand breaks in rice., We further demonstrated that phosphorylation of H2AX in PMCs did not depend on OsATM, in contrast to the situation in somatic cells
- HEI10, OsATM, OsATM safeguards accurate repair of meiotic double-strand breaks in rice., Moreover, the removal of OsDMC1 from chromosomes in Osatm PMCs was delayed and the number of HEI10 foci (markers of interference-sensitive CO intermediates) decreased
- OsATM, OsDMC1~DMC1B~OsDMC1B, OsATM safeguards accurate repair of meiotic double-strand breaks in rice., Aberrant chromosome associations disappeared in Osspo11-1 Osatm-1 double mutants and more severe defects were observed in Osdmc1 Osatm, suggesting that OsATM functions downstream of OsSPO11-1-catalyzed double-strand break (DSB) formation and in parallel with OsDMC1-mediated homologous recombination
- OsATM, OsDMC1~DMC1B~OsDMC1B, OsATM safeguards accurate repair of meiotic double-strand breaks in rice., Moreover, the removal of OsDMC1 from chromosomes in Osatm PMCs was delayed and the number of HEI10 foci (markers of interference-sensitive CO intermediates) decreased
- OsATM, OsSPO11-1~OsTOP6A1, OsATM safeguards accurate repair of meiotic double-strand breaks in rice., Aberrant chromosome associations disappeared in Osspo11-1 Osatm-1 double mutants and more severe defects were observed in Osdmc1 Osatm, suggesting that OsATM functions downstream of OsSPO11-1-catalyzed double-strand break (DSB) formation and in parallel with OsDMC1-mediated homologous recombination
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