- Information
- Symbol: OsBRCA2
- MSU: LOC_Os01g07110
- RAPdb: Os01g0164800,Os01g0164900
- Publication
- Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells, 2020, Front Plant Sci.
- OsRAD51 Plays a Vital Role in Promoting Homologous Recombination in Rice Meiosis., 2022, Int J Mol Sci.
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Genbank accession number
- Key message
- Osbrca2 mutant plants exhibit normal vegetative growth but experience complete male and female sterility as a consequence of severe meiotic defects
- These results indicate that OsBRCA2 is essential for facilitating the loading of OsRAD51 and OsDMC1 onto resected ends of programmed double-strand breaks (DSB) during meiosis to promote single-end invasions of homologous chromosomes and accurate recombination
- Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells
- In the absence of OsBRCA2, localization to the meiotic chromosome axes of the strand-invasion proteins OsRAD51 and OsDMC1 is severely reduced and in vitro OsBRCA2 directly interacts with OsRAD51 and OsDMC1
- Connection
- OsBRCA2, OsDMC1~DMC1B~OsDMC1B, Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells, In the absence of OsBRCA2, localization to the meiotic chromosome axes of the strand-invasion proteins OsRAD51 and OsDMC1 is severely reduced and in vitro OsBRCA2 directly interacts with OsRAD51 and OsDMC1
- OsBRCA2, OsDMC1~DMC1B~OsDMC1B, Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells, These results indicate that OsBRCA2 is essential for facilitating the loading of OsRAD51 and OsDMC1 onto resected ends of programmed double-strand breaks (DSB) during meiosis to promote single-end invasions of homologous chromosomes and accurate recombination
- OsBRCA2, OsRad51~OsRad51A1~COLD11, Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells, In the absence of OsBRCA2, localization to the meiotic chromosome axes of the strand-invasion proteins OsRAD51 and OsDMC1 is severely reduced and in vitro OsBRCA2 directly interacts with OsRAD51 and OsDMC1
- OsBRCA2, OsRad51~OsRad51A1~COLD11, Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells, These results indicate that OsBRCA2 is essential for facilitating the loading of OsRAD51 and OsDMC1 onto resected ends of programmed double-strand breaks (DSB) during meiosis to promote single-end invasions of homologous chromosomes and accurate recombination
- OsBRCA2, OsRad51~OsRad51A1~COLD11, OsRAD51 Plays a Vital Role in Promoting Homologous Recombination in Rice Meiosis., In addition, both OsRAD51 and OsDMC1 can interact with OsFIGL1 and OsBRCA2, two important components in rice meiosis
- OsBRCA2, OsDMC1~DMC1B~OsDMC1B, OsRAD51 Plays a Vital Role in Promoting Homologous Recombination in Rice Meiosis., In addition, both OsRAD51 and OsDMC1 can interact with OsFIGL1 and OsBRCA2, two important components in rice meiosis
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