- Information
- Symbol: RAD51C
- MSU: LOC_Os01g39630
- RAPdb: Os01g0578000
- Publication
- The rice RAD51C gene is required for the meiosis of both female and male gametocytes and the DNA repair of somatic cells, 2012, J Exp Bot.
- OsRAD51D promotes homologous pairing and recombination by preventing nonhomologous interactions in rice meiosis , 2020, New Phytol..
- Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells, 2020, Front Plant Sci.
- Genbank accession number
- Key message
- These results suggest that RAD51C is essential for reproductive development by regulating meiosis as well as for DNA damage repair in somatic cells
- The rice RAD51C gene is required for the meiosis of both female and male gametocytes and the DNA repair of somatic cells
- Transferring RAD51C to the RAD51C-KO line restored fertility
- The RAD51C-KO line showed no obvious difference from wild-type plants in mitosis in the anther wall cells, which was consistent with the observation that the RAD51C-KO line did not have obviously abnormal morphology during vegetative development
- Cytological analyses showed that the sterility of RAD51C-KO plants was associated with abnormal early meiotic processes in both megasporocytes and pollen mother cells (PMCs)
- Knockout (KO) of RAD51C resulted in both female and male sterility in rice
- Connection
- RAD51C, XRCC3, XRCC3 is essential for proper double-strand break repair and homologous recombination in rice meiosis., Moreover, abnormal chromosome localization of RAD51C, DMC1, ZEP1, ZIP4, and MER3 was observed in xrcc3
- MOF, RAD51C, MEIOTIC F-BOX Is Essential for Male Meiotic DNA Double Strand Break Repair in Rice., The recruitment of Completion of meiosis I (COM1) and Radiation sensitive51C (RAD51C) to DSBs is severely compromised in mutant meiocytes, indicating that MOF is crucial for DSB end-processing and repair
Prev Next