OsMDH1

• Symbol: OsMDH1
• MSU: LOC_Os01g61380
• RAPdb: Os01g0829800

• Rice Plastidial NAD-Dependent Malate Dehydrogenase 1 Negatively Regulates Salt Stress Response by Reducing the Vitamin B6 Content., 2019, Plant Biotechnol J.

Genbank accession number

• The OsMDH1 was expressed in different tissues of rice plants including leaf, leaf sheath, panicle, glume, bud, root, and stem and was induced in the presence of NaCl
• Transient expression of OsMDH1-GFP in rice protoplasts showed that OsMDH1 localizes to chloroplast
• In this study, we identified a new loss-of-function osmdh1 mutant displaying salt stress-tolerant phenotype
• Transgenic rice plants overexpressing OsMDH1 (OsMDH1OX) displayed a salt stress-sensitive phenotype
• Moreover, the pyridoxine content was higher in the osmdh1 mutant and lower in OsMDH1OX plants than in the NIP plants under the salt stress, indicating that OsMDH1 negatively regulates salt stress-induced pyridoxine accumulation
• Together, our results establish a novel, negative regulatory role of OsMDH1 in salt stress tolerance by affecting vitamin B6 content of rice tissues