OsZIP1

• Symbol: OsZIP1
• MSU: LOC_Os01g74110
• RAPdb: Os01g0972200

• Rice plants take up iron as an Fe3+-phytosiderophore and as Fe2+, 2006, Plant J.
• OsZIP4, a novel zinc-regulated zinc transporter in rice, 2005, J Exp Bot.
• Expression profiling of Oryza sativa metal homeostasis genes in different rice cultivars using a cDNA macroarray, 2007, Plant Physiol Biochem.
• Differential Metal Selectivity and Gene Expression of Two Zinc Transporters from Rice, 2003, Plant Physiol.
• Cytokinin-dependent regulatory module underlies the maintenance of zinc nutrition in rice., 2019, New Phytol.
• OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice., 2019, BMC Plant Biol.
• Comparative transcriptome profile analysis of rice varieties with different tolerance to zinc deficiency, 2020, Plant Biol (Stuttg).

Genbank accession number

• Transgenic rice overexpressing OsZIP1 grew better under excess metal stress but accumulated less of the metals in plants
• We further identified the DNA methylation of histone H3K9me2 of OsZIP1 and found that OsZIP1 locus, whose transcribed regions imbed a 242 bp sequence, is demethylated, suggesting that epigenetic modification is likely associated with OsZIP1 function under Cd stress
• OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice.
• In this report, we provided evidence that OsZIP1 is a metal-detoxified transporter through preventing excess Zn, Cu and Cd accumulation in rice
• OsZIP1 is a transporter that is required for detoxification of excess Zn, Cu and Cd in rice
• Expression of OsZIP-GFP fusion in rice protoplasts and tobacco leaves shows that OsZIP1 resides in the endoplasmic reticulum (ER) and plasma membrane (PM)

• OsZIP1, ZN, OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice., In this report, we provided evidence that OsZIP1 is a metal-detoxified transporter through preventing excess Zn, Cu and Cd accumulation in rice
• OsZIP1, ZN, OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice., OsZIP1 is abundantly expressed in roots throughout the life span and sufficiently induced by excess Zn, Cu and Cd but not by Mn and Fe at transcriptional and translational levels
• OsZIP1, ZN, OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice., The yeast (Saccharomyces cerevisiae) complementation test shows that expression of OsZIP1 reduced Zn accumulation
• OsZIP1, ZN, OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice., These results suggest OsZIP1 is able to function as a metal exporter in rice when Zn, Cu and Cd are excess in environment
• OsZIP1, ZN, OsZIP1 functions as a metal efflux transporter limiting excess zinc, copper and cadmium accumulation in rice., OsZIP1 is a transporter that is required for detoxification of excess Zn, Cu and Cd in rice