OsBip1

• Symbol: OsBip1
• MSU: LOC_Os02g02410
• RAPdb: Os02g0115900

• Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, 2012, Planta.
• Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice, 2012, Plant J.
• Expression of ER quality control-related genes in response to changes in BiP1 levels in developing rice endosperm, 2011, Plant J.
• Overexpression of the endoplasmic reticulum chaperone BiP3 regulates XA21-mediated innate immunity in rice, 2010, PLoS One.
• OsFes1C, a potential nucleotide exchange factor for OsBiP1, is involved in the ER and salt stress responses , 2021, Plant Physiol.

Genbank accession number

• When the subcellular localization of OsBiP4&5 was investigated in seed endosperm cells under the ER stress condition, OsBiP4&5 were localized to the ER, but did not participate in ER-derived protein body (PB-I) formation in a different manner to OsBiP1

• OsBip1, OsBiP4, Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, OsBiP1 is constitutively expressed in various tissues, whereas the expression of OsBiP4 and OsBiP5 (OsBiP4&5) is not detected in any tissue under normal conditions
• OsBip1, OsBiP4, Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, However, expression of OsBiP4&5 was highly and specifically activated under ER stress conditions induced by DTT treatment, OsBiP1 knockdown, OsBiP1 overexpression, OsIRE1 overexpression, or various exogenous recombinant proteins in transgenic rice
• OsBip1, OsBiP4, Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, When the subcellular localization of OsBiP4&5 was investigated in seed endosperm cells under the ER stress condition, OsBiP4&5 were localized to the ER, but did not participate in ER-derived protein body (PB-I) formation in a different manner to OsBiP1
• OsBip1, OsBiP4, Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, Taken together, these results suggest that OsBiP4&5 are ER stress-related BiP proteins that are regulated by OsIRE1/OsbZIP50 pathway and that they may have a distinct function from that of OsBiP1 in rice
• IRE1~OsIRE1, OsBip1, Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, However, expression of OsBiP4&5 was highly and specifically activated under ER stress conditions induced by DTT treatment, OsBiP1 knockdown, OsBiP1 overexpression, OsIRE1 overexpression, or various exogenous recombinant proteins in transgenic rice
• IRE1~OsIRE1, OsBip1, Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, Taken together, these results suggest that OsBiP4&5 are ER stress-related BiP proteins that are regulated by OsIRE1/OsbZIP50 pathway and that they may have a distinct function from that of OsBiP1 in rice
• OsBip1, OsBiP5, Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice, OsBiP1 is constitutively expressed in various tissues, whereas the expression of OsBiP4 and OsBiP5 (OsBiP4&5) is not detected in any tissue under normal conditions
• NEF~Fes1-like, OsBip1, OsFes1C, a potential nucleotide exchange factor for OsBiP1, is involved in the ER and salt stress responses , OsFes1C interacts directly with OsBiP1 and the interaction is inhibited by ATP but promoted by ADP, suggesting that OsFes1C acts as a potential NEF of OsBiP1 in vivo
• OsBip1, OsbZIP60, OsbZIP60-mediated unfolded protein response regulates grain chalkiness in rice., Notably, the expression of unfolded protein response (UPR) genes, such as OsbZIP50, OsBiP1, OsBiP2 and OsBiP3, is up-regulated in the endosperm cells of osbzip60, and overexpression of all these UPR genes causes various degrees of chalkiness
• OsBip1, OsbZIP60, OsbZIP60-mediated unfolded protein response regulates grain chalkiness in rice., Furthermore, OsbZIP60 is found to activate the expression of key genes related to grain chalkiness, such as GPA3, FSE1, FLO7, Chalk5, OsNF-YB1, and OsPK2, whose expression is significantly suppressed in osbzip60 and overexpression lines of OsbZIP50, OsBiP1, OsBiP2, and OsBiP3