- Information
- Symbol: OsCUL3a,OsSPL88
- MSU: LOC_Os02g51180
- RAPdb: Os02g0746000
- Publication
- OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., 2017, Plant Cell.
- OsCUL3a-associated molecular switches have functions in cell metabolism, cell death, and disease resistance., 2020, J Agric Food Chem.
- OsSPL88 Encodes a Cullin Protein that Regulates Rice Growth and Development., 2022, Front Genet.
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Genbank accession number
- Key message
- The rice lesion mimic mutant oscul3a displays a significant increase in the accumulation of flg22- and chitin-induced reactive oxygen species, and in pathogenesis-related gene expression as well as resistance to Magnaporthe oryzae and Xanthomonas oryzae pv
- OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice.
- Here, we show that rice OsCUL3a is important for the regulation of cell death and immunity
- Strikingly, OsCUL3a interacts with and degrades OsNPR1, which acts as a positive regulator of cell death in rice
- Our data demonstrate that OsCUL3a negatively regulates cell death and immunity by degrading OsNPR1 in rice
- We cloned the OsCUL3a gene via a map-based strategy and found that the lesion mimic phenotype of oscul3a is associated with the early termination of OsCUL3a protein
- Furthermore, the oscul3a osnpr1 double mutant does not exhibit the lesion mimic phenotype of the oscul3a mutant
- In oscul3a (oscullin3a) mutants, OsCUL3a-associated molecular switches are responsible for disrupted cell metabolism that leads to increased total lipid content in rice grain, a late accumulation of H2O2 in leaves, enhanced Xoo disease resistance, and suppressed panicle and first internode growth
- In oscul3a mutants, PRM confirmed up-regulated molecular switch proteins include lipoxygenases (CM-LOX1 and CM-LOX2), suggesting a novel connection between ferroptosis and rice lesion mimic formation
- OsSPL88 Encodes a Cullin Protein that Regulates Rice Growth and Development.
- Connection
- OsCUL3a~OsSPL88, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice.
- OsCUL3a~OsSPL88, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Strikingly, OsCUL3a interacts with and degrades OsNPR1, which acts as a positive regulator of cell death in rice
- OsCUL3a~OsSPL88, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Accumulation of OsNPR1 protein is greater in the oscul3a mutant than in the wild type
- OsCUL3a~OsSPL88, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Furthermore, the oscul3a osnpr1 double mutant does not exhibit the lesion mimic phenotype of the oscul3a mutant
- OsCUL3a~OsSPL88, OsNPR1~NH1, OsCUL3a Negatively Regulates Cell Death and Immunity by Degrading OsNPR1 in Rice., Our data demonstrate that OsCUL3a negatively regulates cell death and immunity by degrading OsNPR1 in rice
- NH3~OsNPR3, OsCUL3a~OsSPL88, OsCUL3a-associated molecular switches have functions in cell metabolism, cell death, and disease resistance., Together, these results describe a network that regulates plant growth, disease resistance, and grain quality that includes the E3 ligase OsCUL3a, cell metabolism-associated molecular switches, and immunity switches OsNPR1 and OsNPR3
- OsCUL3a~OsSPL88, OsNPR1~NH1, OsCUL3a-associated molecular switches have functions in cell metabolism, cell death, and disease resistance., Together, these results describe a network that regulates plant growth, disease resistance, and grain quality that includes the E3 ligase OsCUL3a, cell metabolism-associated molecular switches, and immunity switches OsNPR1 and OsNPR3
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