PAIR1

2015-01-20 | Categories genes  | Tags meiosis  tapetum  meiotic  flower  anther  sterility 

• Information
  • Symbol: PAIR1
  • MSU: LOC_Os03g01590
  • RAPdb: Os03g0106300
• Publication
  • The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, 2012, Plant J.
  • The novel gene HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS1 of rice encodes a putative coiled-coil protein required for homologous chromosome pairing in meiosis, 2004, Plant Cell.
  • Central region component1, a novel synaptonemal complex component, is essential for meiotic recombination initiation in rice, 2013, Plant Cell.
• Genbank accession number
  • AB158462
• Key message
  • Transcripts of UDT1, which functions in tapetum development during early meiosis, were reduced in dtm1 anthers, as were those of PAIR1, which is involved in chromosome pairing and synapsis during meiosis
  • These results, together with their mutant phenotypes, suggest that DTM1 plays important roles in the ER membrane during early tapetum development, functioning after MSP1 and before UDT1, and also in meiocyte development, after MEL1 and before PAIR1
  • However, chromosomal fragmentation frequent in plant meiotic mutants was never observed in all of the pair1 meiocytes
  • CRC1 interacts with homologous pairing aberration in rice meiosis1 (PAIR1) in vitro, suggesting that these proteins act as a complex to promote DSB formation
  • Expression of the PAIR1 gene was detected in the early stages of flower development, in which the majority of the sporocytes had not entered meiosis
  • Moreover, transcripts of DTM1 were reduced in msp1 mutant anthers, but not in udt1 and pair1 mutants
  • We have identified and characterized a novel gene, PAIR1 (HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS1), required for homologous chromosome pairing and cytokinesis in male and female meiocytes of rice (Oryza sativa)
  • The pair1 mutation, tagged by the endogenous retrotransposon Tos17, exhibited meiosis-specific defects and resulted in complete sterility in male and female gametes
  • These observations clarify that the PAIR1 protein plays an essential role in establishment of homologous chromosome pairing in rice meiosis
• Connection
  • DTM1, PAIR1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, Transcripts of UDT1, which functions in tapetum development during early meiosis, were reduced in dtm1 anthers, as were those of PAIR1, which is involved in chromosome pairing and synapsis during meiosis
  • DTM1, PAIR1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, Moreover, transcripts of DTM1 were reduced in msp1 mutant anthers, but not in udt1 and pair1 mutants
  • DTM1, PAIR1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, These results, together with their mutant phenotypes, suggest that DTM1 plays important roles in the ER membrane during early tapetum development, functioning after MSP1 and before UDT1, and also in meiocyte development, after MEL1 and before PAIR1
  • MEL1, PAIR1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, These results, together with their mutant phenotypes, suggest that DTM1 plays important roles in the ER membrane during early tapetum development, functioning after MSP1 and before UDT1, and also in meiocyte development, after MEL1 and before PAIR1
  • PAIR1, Udt1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, Transcripts of UDT1, which functions in tapetum development during early meiosis, were reduced in dtm1 anthers, as were those of PAIR1, which is involved in chromosome pairing and synapsis during meiosis
  • PAIR1, Udt1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, Moreover, transcripts of DTM1 were reduced in msp1 mutant anthers, but not in udt1 and pair1 mutants
  • PAIR1, Udt1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, These results, together with their mutant phenotypes, suggest that DTM1 plays important roles in the ER membrane during early tapetum development, functioning after MSP1 and before UDT1, and also in meiocyte development, after MEL1 and before PAIR1
  • OsMSP1~MSP1~OsTMS15, PAIR1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, Moreover, transcripts of DTM1 were reduced in msp1 mutant anthers, but not in udt1 and pair1 mutants
  • OsMSP1~MSP1~OsTMS15, PAIR1, The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 DTM1 is required for early tapetum development and meiosis, These results, together with their mutant phenotypes, suggest that DTM1 plays important roles in the ER membrane during early tapetum development, functioning after MSP1 and before UDT1, and also in meiocyte development, after MEL1 and before PAIR1
  • CRC1, PAIR1, Central region component1, a novel synaptonemal complex component, is essential for meiotic recombination initiation in rice, CRC1 interacts with homologous pairing aberration in rice meiosis1 (PAIR1) in vitro, suggesting that these proteins act as a complex to promote DSB formation
  • PAIR1, ZYGO1, The F-box protein ZYGO1 mediates bouquet formation to promote homologous pairing, synapsis, and recombination in rice meiosis., The suppressed telomere clustering in homologous pairing aberration in rice meiosis 1 (pair1) zygo1 and rice completion of meiotic recombination (Oscom1) zygo1 double mutants, together with the altered localization of OsSAD1 (a SUN protein associated with the nuclear envelope) in zygo1 showed that ZYGO1 has a significant function in bouquet formation
  • OsRAD51D, PAIR1, OsRAD51D promotes homologous pairing and recombination by preventing non-homologous interactions in rice meiosis., Observations from the Osrad51d pair1 and Osrad51d ku70 double mutants further demonstrate that non-homologous interactions require DSB formation, but do not depend on the KU70-mediated repair pathway
  • OsRAD51D, PAIR1, OsRAD51D promotes homologous pairing and recombination by preventing nonhomologous interactions in rice meiosis , Observations from the Osrad51d pair1 and Osrad51d ku70 double mutants further demonstrate that nonhomologous interactions require double-strand break formation but do not depend on the KU70-mediated repair pathway

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