OsDSK2a

• Symbol: OsDSK2a
• MSU: LOC_Os03g03920
• RAPdb: Os03g0131300

• The Ubiquitin-Binding Protein OsDSK2a Mediates Seedling Growth and Salt Responses by Regulating Gibberellin Metabolism in Rice., 2019, Plant Cell.

Genbank accession number

• The Ubiquitin-Binding Protein OsDSK2a Mediates Seedling Growth and Salt Responses by Regulating Gibberellin Metabolism in Rice.
• Here, we demonstrate that the novel UBL-UBA protein OsDSK2a (DOMINANT SUPPRESSOR of KAR2) mediates seedling growth and salt responses in rice (Oryza sativa)
• Bioactive GA levels were reduced and plant growth was retarded in the osdsk2a mutant
• Thus, OsDSK2a and EUI play opposite roles in regulating plant growth under salt stress by affecting GA metabolism
• Downregulation of the ubiquitin-binding receptor OsDSK2a increases EUI accumulation, which promotes GA metabolism and reduces plant growth under salt stress
• Through analysis of osdsk2a, a mutant with retarded seedling growth, as well as in vitro and in vivo assays, we demonstrated that OsDSK2a combines with polyubiquitin chains and interacts with the gibberellin (GA)-deactivating enzyme ELONGATED UPPERMOST INTERNODE (EUI), resulting in its degradation through the ubiquitin-proteasome system
• OsDSK2a levels decreased in plant under salt stress
• Moreover, EUI accumulated under salt stress more rapidly in osdsk2a than in wild-type plants