GUDK

• Symbol: GUDK
• MSU: LOC_Os03g08170
• RAPdb: Os03g0179400

• Rice GROWTH UNDER DROUGHT KINASE is required for drought tolerance and grain yield under normal and drought stress conditions., 2014, Plant Physiol.
• Regulation of grain yield in rice under well-watered and drought stress conditions by GUDK., 2015, Plant Signal Behav.

Genbank accession number

• The gudk mutants interestingly showed a significant reduction in grain yield, both under normal well-watered conditions and under drought stress at the reproductive stage
• Loss-of-function gudk mutant lines exhibit sensitivity to salinity, osmotic stress, and abscisic acid treatment at the seedling stage, and a reduction in photosynthesis and plant biomass under controlled drought stress at the vegetative stage
• Phosphoproteome profiling of the mutant followed by in vitro assays identified the transcription factor APETALA2/ETHYLENE RESPONSE FACTOR OsAP37 as a phosphorylation target of GUDK
• We propose that GUDK mediates drought stress signaling through phosphorylation and activation of OsAP37, resulting in transcriptional activation of stress-regulated genes, which impart tolerance and improve yield under drought
• Our transactivation assays confirmed that GUDK is required for activation of stress genes by OsAP37
• GUDK is induced under several stresses and its loss-of-function increased the sensitivity of rice seedlings to salinity, osmotic stress, and abscisic acid treatment
• In addition to reduced tolerance of gudk mutant plants to drought stress at vegetative stage, a significant reduction in grain yield was observed under well-watered and drought stress conditions at reproductive stage
• Thus, our results suggest that GUDK has the potential to regulate grain yield both under favorable and unfavorable conditions
• Gene co-expression analysis supports the role of GUDK in regulating important biological processes both under control and stress conditions

• GUDK, OsAP37, Rice GROWTH UNDER DROUGHT KINASE is required for drought tolerance and grain yield under normal and drought stress conditions., Phosphoproteome profiling of the mutant followed by in vitro assays identified the transcription factor APETALA2/ETHYLENE RESPONSE FACTOR OsAP37 as a phosphorylation target of GUDK
• GUDK, OsAP37, Rice GROWTH UNDER DROUGHT KINASE is required for drought tolerance and grain yield under normal and drought stress conditions., Our transactivation assays confirmed that GUDK is required for activation of stress genes by OsAP37
• GUDK, OsAP37, Rice GROWTH UNDER DROUGHT KINASE is required for drought tolerance and grain yield under normal and drought stress conditions., We propose that GUDK mediates drought stress signaling through phosphorylation and activation of OsAP37, resulting in transcriptional activation of stress-regulated genes, which impart tolerance and improve yield under drought
• GUDK, OsAP37, Regulation of grain yield in rice under well-watered and drought stress conditions by GUDK., Recently, we functionally characterized a receptor-like cytoplasmic kinase, named GROWTH UNDER DROUGHT KINASE (GUDK), revealing its role in regulating grain yield under well-watered and drought stress conditions by transphosphorylating the OsAP37 transcription factor