- Information
- Symbol: OsSPK1
- MSU: LOC_Os03g21080
- RAPdb: Os03g0328000
- Publication
- Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., 2018, Proc Natl Acad Sci U S A.
- The OsSPK1-OsRac1-RAI1 defense signaling pathway is shared by two distantly related NLR proteins in rice blast resistance., 2021, Plant Physiol.
-
Genbank accession number
- Key message
- Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity.
- OsSPK1 contributes to signaling by two disease-resistance genes, Pit and Pia, against the rice blast fungus Magnaporthe oryzae and facilitates OsRac1 activation in vitro and in vivo
- Overall, we conclude that OsSPK1 is a direct and key signaling target of Pit-mediated immunity
- OsSPK1 activates the small GTPase OsRac1, which in turn transduces the signal to the transcription factor RAC IMMUNITY1 (RAI1)
- We found that in blast resistance mediated by the NLR PIRICULARIA ORYZAE RESISTANCE IN DIGU 3 (PID3), the guanine nucleotide exchange factor OsSPK1 works downstream of PID3
- Connection
- GLUP6~GEF, OsSPK1, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity.
- OsRac1, OsSPK1, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity.
- OsRac1, OsSPK1, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., Here, we identified OsSPK1, a DOCK family guanine nucleotide exchange factor, as an interactor of Pit and activator for OsRac1
- OsRac1, OsSPK1, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., OsSPK1 contributes to signaling by two disease-resistance genes, Pit and Pia, against the rice blast fungus Magnaporthe oryzae and facilitates OsRac1 activation in vitro and in vivo
- OsRac1, OsSPK1, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., The CC domain of Pit is required for its binding to OsSPK1, OsRac1 activation, and the induction of cell death
- OsSPK1, Pit, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity.
- OsSPK1, Pit, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., Here, we identified OsSPK1, a DOCK family guanine nucleotide exchange factor, as an interactor of Pit and activator for OsRac1
- OsSPK1, Pit, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., OsSPK1 contributes to signaling by two disease-resistance genes, Pit and Pia, against the rice blast fungus Magnaporthe oryzae and facilitates OsRac1 activation in vitro and in vivo
- OsSPK1, Pit, Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity., The CC domain of Pit is required for its binding to OsSPK1, OsRac1 activation, and the induction of cell death
- OsSPK1, RAI1, The OsSPK1-OsRac1-RAI1 defense signaling pathway is shared by two distantly related NLR proteins in rice blast resistance., OsSPK1 activates the small GTPase OsRac1, which in turn transduces the signal to the transcription factor RAC IMMUNITY1 (RAI1)
- OsRac1, OsSPK1, The OsSPK1-OsRac1-RAI1 defense signaling pathway is shared by two distantly related NLR proteins in rice blast resistance., OsSPK1 activates the small GTPase OsRac1, which in turn transduces the signal to the transcription factor RAC IMMUNITY1 (RAI1)
- OsSPK1, Pi25~Pid3, The OsSPK1-OsRac1-RAI1 defense signaling pathway is shared by two distantly related NLR proteins in rice blast resistance., We found that in blast resistance mediated by the NLR PIRICULARIA ORYZAE RESISTANCE IN DIGU 3 (PID3), the guanine nucleotide exchange factor OsSPK1 works downstream of PID3
Prev Next