- Information
- Symbol: OsIRT1
- MSU: LOC_Os03g46470
- RAPdb: Os03g0667500
- Publication
- Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, 2011, J Exp Bot.
- Rice plants take up iron as an Fe3+-phytosiderophore and as Fe2+, 2006, Plant J.
- OsZIP4, a novel zinc-regulated zinc transporter in rice, 2005, J Exp Bot.
- Cloning an iron-regulated metal transporter from rice, 2002, J Exp Bot.
- Isolation and characterization of IRO2, a novel iron-regulated bHLH transcription factor in graminaceous plants, 2006, J Exp Bot.
- A receptor-like protein RMC is involved in regulation of iron acquisition in rice, 2013, J Exp Bot.
- Over-expression of OsIRT1 leads to increased iron and zinc accumulations in rice, 2009, Plant Cell Environ.
- The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, 2009, Plant J.
- OsARF12, a transcription activator on auxin response gene, regulates root elongation and affects iron accumulation in rice Oryza sativa, 2012, New Phytol.
- Iron deficiency enhances cadmium uptake and translocation mediated by the Fe2+transporters OsIRT1 and OsIRT2 in rice, 2006, Soil Science and Plant Nutrition.
- Mutational reconstructed ferric chelate reductase confers enhanced tolerance in rice to iron deficiency in calcareous soil, 2007, Proc Natl Acad Sci U S A.
- Comparative transcriptome profile analysis of rice varieties with different tolerance to zinc deficiency, 2020, Plant Biol (Stuttg).
- Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, 2020, PLoS One.
- Genbank accession number
- Key message
- RNA interference of OsIRO2 in transgenic rice showed that ethylene acted via this transcription factor to induce the expression of OsNAS1, OsNAS2, OsYSL15, and OsIRT1
- This suggests that OsIRT1 is a functional metal transporter for iron, and is actively engaged in Fe uptake from soils, especially under limiting conditions
- The knockout of OsARF12 also altered the abundance of mitochondrial iron-regulated (OsMIR), iron (Fe)-regulated transporter1 (OsIRT1) and short postembryonic root1 (OsSPR1) in roots of rice, and resulted in lower Fe content
- In spite of being a Strategy II plant, however, rice (Oryza sativa) contains the previously identified Fe2+ transporter OsIRT1
- Real-time PCR analysis revealed that OsIRT1 and OsIRT2 are expressed predominantly in roots, and these transporters are induced by low-Fe conditions
- Over-expression of OsIRT1 leads to increased iron and zinc accumulations in rice
- Northern blot analysis revealed that OsIRT1 mRNA was predominantly expressed in roots and was induced by Fe and Cu‐deficiency
- Yeast mutants expressing OsIRT1 and OsIRT2, which encode the rice Fe2+ transporter, became more sensitive to Cd, suggesting that Cd was absorbed by OsIRT1 and OsIRT2
- Iron deficiency enhances cadmium uptake and translocation mediated by the Fe2+transporters OsIRT1 and OsIRT2 in rice
- A yeast Fe3+ chelate-reductase gene refre1/372, selected for better performance at high pH, was fused to the promoter of the Fe-regulated transporter, OsIRT1, and introduced into rice plants
- We generated transgenic rice plants over-expressing OsIRT1 to evaluate its functional roles in metal homeostasis
- OsIRT1 promoter-GUS analysis revealed that OsIRT1 is expressed in the epidermis and exodermis of the elongating zone and in the inner layer of the cortex of the mature zone of Fe-deficient roots
- Four distinct genes, OsZIP4, OsZIP5, OsZIP6, and OsZIP7 that exhibit sequence similarity to the rice ferrous ion transporter, OsIRT1, were isolated
- This demonstrates that OsIRT1 can be used for enhancing micronutrient levels in rice grains
- When expressed in yeast cells, OsIRT1 cDNA reversed the growth defects of the yeast iron‐uptake mutant
- Connection
- OsIRT1, OsNAS2, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, RNA interference of OsIRO2 in transgenic rice showed that ethylene acted via this transcription factor to induce the expression of OsNAS1, OsNAS2, OsYSL15, and OsIRT1
- OsIRT1, OsNAS2, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, Gene expression analysis of rice iron-regulated bHLH transcription factor OsIRO2, nicotianamine synthases 1 and 2 (NAS1 and NAS2), yellow-stripe like transporter 15 (YSL15) and iron-regulated transporter (IRT1) indicated that ethylene caused an increase in transcript abundance of both Fe (II) and Fe (III)-phytosiderophore uptake systems
- OsIRT1, OsNAS1, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, RNA interference of OsIRO2 in transgenic rice showed that ethylene acted via this transcription factor to induce the expression of OsNAS1, OsNAS2, OsYSL15, and OsIRT1
- OsIRT1, OsNAS1, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, Gene expression analysis of rice iron-regulated bHLH transcription factor OsIRO2, nicotianamine synthases 1 and 2 (NAS1 and NAS2), yellow-stripe like transporter 15 (YSL15) and iron-regulated transporter (IRT1) indicated that ethylene caused an increase in transcript abundance of both Fe (II) and Fe (III)-phytosiderophore uptake systems
- OsIRO2~OsbHLH056, OsIRT1, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, Gene expression analysis of rice iron-regulated bHLH transcription factor OsIRO2, nicotianamine synthases 1 and 2 (NAS1 and NAS2), yellow-stripe like transporter 15 (YSL15) and iron-regulated transporter (IRT1) indicated that ethylene caused an increase in transcript abundance of both Fe (II) and Fe (III)-phytosiderophore uptake systems
- OsIRO2~OsbHLH056, OsIRT1, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, RNA interference of OsIRO2 in transgenic rice showed that ethylene acted via this transcription factor to induce the expression of OsNAS1, OsNAS2, OsYSL15, and OsIRT1
- OsIRT1, OsYSL15, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, RNA interference of OsIRO2 in transgenic rice showed that ethylene acted via this transcription factor to induce the expression of OsNAS1, OsNAS2, OsYSL15, and OsIRT1
- OsIRT1, OsYSL15, Ethylene is involved in the regulation of iron homeostasis by regulating the expression of iron-acquisition-related genes in Oryza sativa, Gene expression analysis of rice iron-regulated bHLH transcription factor OsIRO2, nicotianamine synthases 1 and 2 (NAS1 and NAS2), yellow-stripe like transporter 15 (YSL15) and iron-regulated transporter (IRT1) indicated that ethylene caused an increase in transcript abundance of both Fe (II) and Fe (III)-phytosiderophore uptake systems
- OsIRT1, OsIRT2, Rice plants take up iron as an Fe3+-phytosiderophore and as Fe2+, In this study, we isolated the OsIRT2 gene from rice, which is highly homologous to OsIRT1
- OsIRT1, OsIRT2, Rice plants take up iron as an Fe3+-phytosiderophore and as Fe2+, Real-time PCR analysis revealed that OsIRT1 and OsIRT2 are expressed predominantly in roots, and these transporters are induced by low-Fe conditions
- OsIRT1, OsIRT2, Rice plants take up iron as an Fe3+-phytosiderophore and as Fe2+, OsIRT1- and OsIRT2-green fluorescent protein fusion proteins localized to the plasma membrane when transiently expressed in onion (Allium cepa L
- OsIRT1, OsZIP5, OsZIP4, a novel zinc-regulated zinc transporter in rice, Four distinct genes, OsZIP4, OsZIP5, OsZIP6, and OsZIP7 that exhibit sequence similarity to the rice ferrous ion transporter, OsIRT1, were isolated
- OsIRT1, OsZIP4, OsZIP4, a novel zinc-regulated zinc transporter in rice, Four distinct genes, OsZIP4, OsZIP5, OsZIP6, and OsZIP7 that exhibit sequence similarity to the rice ferrous ion transporter, OsIRT1, were isolated
- OsAPT1~APRT, OsIRT1, Isolation and characterization of IRO2, a novel iron-regulated bHLH transcription factor in graminaceous plants, Sequences similar to the OsIRO2-binding sequence were found upstream of several genes that are involved in Fe acquisition, such as OsNAS1, OsNAS3, OsIRT1, OsFDH, OsAPT1, and IDS3
- FDH, OsIRT1, Isolation and characterization of IRO2, a novel iron-regulated bHLH transcription factor in graminaceous plants, Sequences similar to the OsIRO2-binding sequence were found upstream of several genes that are involved in Fe acquisition, such as OsNAS1, OsNAS3, OsIRT1, OsFDH, OsAPT1, and IDS3
- OsIRO2~OsbHLH056, OsIRT1, Isolation and characterization of IRO2, a novel iron-regulated bHLH transcription factor in graminaceous plants, Sequences similar to the OsIRO2-binding sequence were found upstream of several genes that are involved in Fe acquisition, such as OsNAS1, OsNAS3, OsIRT1, OsFDH, OsAPT1, and IDS3
- OsIRT1, OsNAS3, Isolation and characterization of IRO2, a novel iron-regulated bHLH transcription factor in graminaceous plants, Sequences similar to the OsIRO2-binding sequence were found upstream of several genes that are involved in Fe acquisition, such as OsNAS1, OsNAS3, OsIRT1, OsFDH, OsAPT1, and IDS3
- OsIRT1, OsNAS1, Isolation and characterization of IRO2, a novel iron-regulated bHLH transcription factor in graminaceous plants, Sequences similar to the OsIRO2-binding sequence were found upstream of several genes that are involved in Fe acquisition, such as OsNAS1, OsNAS3, OsIRT1, OsFDH, OsAPT1, and IDS3
- OsIRT1, OsNAS1, A receptor-like protein RMC is involved in regulation of iron acquisition in rice, Several Fe deficiency-responsive genes including OsDMAS1, OsNAS1, OsNAS2, OsNAAT1, OsIRT1, OsYSL15, and OsIRO2 were up- and downregulated in OsRMC-overexpressing and RNAi plants compared with WT rice plants
- OsIRT1, OsNAS2, A receptor-like protein RMC is involved in regulation of iron acquisition in rice, Several Fe deficiency-responsive genes including OsDMAS1, OsNAS1, OsNAS2, OsNAAT1, OsIRT1, OsYSL15, and OsIRO2 were up- and downregulated in OsRMC-overexpressing and RNAi plants compared with WT rice plants
- OsIRO2~OsbHLH056, OsIRT1, A receptor-like protein RMC is involved in regulation of iron acquisition in rice, Several Fe deficiency-responsive genes including OsDMAS1, OsNAS1, OsNAS2, OsNAAT1, OsIRT1, OsYSL15, and OsIRO2 were up- and downregulated in OsRMC-overexpressing and RNAi plants compared with WT rice plants
- OsIRT1, OsRMC~OsRLK, A receptor-like protein RMC is involved in regulation of iron acquisition in rice, Several Fe deficiency-responsive genes including OsDMAS1, OsNAS1, OsNAS2, OsNAAT1, OsIRT1, OsYSL15, and OsIRO2 were up- and downregulated in OsRMC-overexpressing and RNAi plants compared with WT rice plants
- OsIRT1, OsYSL15, A receptor-like protein RMC is involved in regulation of iron acquisition in rice, Several Fe deficiency-responsive genes including OsDMAS1, OsNAS1, OsNAS2, OsNAAT1, OsIRT1, OsYSL15, and OsIRO2 were up- and downregulated in OsRMC-overexpressing and RNAi plants compared with WT rice plants
- OsIRT1, OsNAAT1, A receptor-like protein RMC is involved in regulation of iron acquisition in rice, Several Fe deficiency-responsive genes including OsDMAS1, OsNAS1, OsNAS2, OsNAAT1, OsIRT1, OsYSL15, and OsIRO2 were up- and downregulated in OsRMC-overexpressing and RNAi plants compared with WT rice plants
- OsIRO2~OsbHLH056, OsIRT1, The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, Time-course expression analyses using quantitative reverse-transcriptase PCR revealed that the IDEF1 expression level was positively correlated with the level of induction of the Fe utilization-related genes OsIRO2, OsYSL15, OsIRT1, OsYSL2, OsNAS1, OsNAS2, OsNAS3 and OsDMAS1, just after the onset of Fe starvation
- OsIRT1, OsNAS2, The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, Time-course expression analyses using quantitative reverse-transcriptase PCR revealed that the IDEF1 expression level was positively correlated with the level of induction of the Fe utilization-related genes OsIRO2, OsYSL15, OsIRT1, OsYSL2, OsNAS1, OsNAS2, OsNAS3 and OsDMAS1, just after the onset of Fe starvation
- IDEF1, OsIRT1, The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, Time-course expression analyses using quantitative reverse-transcriptase PCR revealed that the IDEF1 expression level was positively correlated with the level of induction of the Fe utilization-related genes OsIRO2, OsYSL15, OsIRT1, OsYSL2, OsNAS1, OsNAS2, OsNAS3 and OsDMAS1, just after the onset of Fe starvation
- OsIRT1, OsNAS3, The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, Time-course expression analyses using quantitative reverse-transcriptase PCR revealed that the IDEF1 expression level was positively correlated with the level of induction of the Fe utilization-related genes OsIRO2, OsYSL15, OsIRT1, OsYSL2, OsNAS1, OsNAS2, OsNAS3 and OsDMAS1, just after the onset of Fe starvation
- OsIRT1, OsNAS1, The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, Time-course expression analyses using quantitative reverse-transcriptase PCR revealed that the IDEF1 expression level was positively correlated with the level of induction of the Fe utilization-related genes OsIRO2, OsYSL15, OsIRT1, OsYSL2, OsNAS1, OsNAS2, OsNAS3 and OsDMAS1, just after the onset of Fe starvation
- OsIRT1, OsYSL2~CF1, The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, Time-course expression analyses using quantitative reverse-transcriptase PCR revealed that the IDEF1 expression level was positively correlated with the level of induction of the Fe utilization-related genes OsIRO2, OsYSL15, OsIRT1, OsYSL2, OsNAS1, OsNAS2, OsNAS3 and OsDMAS1, just after the onset of Fe starvation
- OsIRT1, OsYSL15, The rice transcription factor IDEF1 is essential for the early response to iron deficiency, and induces vegetative expression of late embryogenesis abundant genes, Time-course expression analyses using quantitative reverse-transcriptase PCR revealed that the IDEF1 expression level was positively correlated with the level of induction of the Fe utilization-related genes OsIRO2, OsYSL15, OsIRT1, OsYSL2, OsNAS1, OsNAS2, OsNAS3 and OsDMAS1, just after the onset of Fe starvation
- OsARF12, OsIRT1, OsARF12, a transcription activator on auxin response gene, regulates root elongation and affects iron accumulation in rice Oryza sativa, The knockout of OsARF12 also altered the abundance of mitochondrial iron-regulated (OsMIR), iron (Fe)-regulated transporter1 (OsIRT1) and short postembryonic root1 (OsSPR1) in roots of rice, and resulted in lower Fe content
- OsIRT1, Osspr1, OsARF12, a transcription activator on auxin response gene, regulates root elongation and affects iron accumulation in rice Oryza sativa, The knockout of OsARF12 also altered the abundance of mitochondrial iron-regulated (OsMIR), iron (Fe)-regulated transporter1 (OsIRT1) and short postembryonic root1 (OsSPR1) in roots of rice, and resulted in lower Fe content
- OsIRT1, OsIRT2, Iron deficiency enhances cadmium uptake and translocation mediated by the Fe2+transporters OsIRT1 and OsIRT2 in rice, Yeast mutants expressing OsIRT1 and OsIRT2, which encode the rice Fe2+ transporter, became more sensitive to Cd, suggesting that Cd was absorbed by OsIRT1 and OsIRT2
- OsIRT1, OsIRT2, Iron deficiency enhances cadmium uptake and translocation mediated by the Fe2+transporters OsIRT1 and OsIRT2 in rice, Iron deficiency enhances cadmium uptake and translocation mediated by the Fe2+transporters OsIRT1 and OsIRT2 in rice
- OsIRT1, OsRab6a, A Small GTPase, OsRab6a, Is Involved in the Regulation of Iron Homeostasis in Rice, Exposure to Fe-deficient medium led to up-regulation of OsIRO2, OsIRT1, OsNAS1 and OsNAS2 in both wild-type and the transgenic rice plants, with the magnitude of up-regulation positively correlated with the expression levels of OsRab6a
- OsIRO2~OsbHLH056, OsIRT1, Enhancement of Iron Acquisition in Rice by the Mugineic Acid Synthase Gene With Ferric Iron Reductase Gene and OsIRO2 Confers Tolerance in Submerged and Nonsubmerged Calcareous Soils., Furthermore, under Fe-limited nonsubmerged calcareous soil condition (a new cultivation condition), IRI lines also conferred enhanced tolerance than NT, lines introducing only the OsIRT1 promoter-refre1/372 or overexpressing OsIRO2, and lines harboring both
- OsIRT1, OsNRAMP5, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Fe, Mn, and Cd transporters such as CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, OsHMA3, and OsNAAT1 regulate uptake of Cd in rice
- OsIRT1, OsNRAMP5, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Meanwhile, application of sufficient doses of Fe and Cd in solution culture increased RE of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 in roots, whereas expression level of OsHMA3 was decreased
- OsIRT1, OsNRAMP5, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, This may be concluded that the Cd increases expression of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 but decreases OsHMA3 expression in rice roots, which resulted in increased Cd uptake in hydroponically grown rice
- OsIRT1, OsNRAMP1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Fe, Mn, and Cd transporters such as CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, OsHMA3, and OsNAAT1 regulate uptake of Cd in rice
- OsIRT1, OsNRAMP1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Meanwhile, application of sufficient doses of Fe and Cd in solution culture increased RE of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 in roots, whereas expression level of OsHMA3 was decreased
- OsIRT1, OsNRAMP1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, This may be concluded that the Cd increases expression of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 but decreases OsHMA3 expression in rice roots, which resulted in increased Cd uptake in hydroponically grown rice
- OsDEF7~CAL1~OsAFP1, OsIRT1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Fe, Mn, and Cd transporters such as CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, OsHMA3, and OsNAAT1 regulate uptake of Cd in rice
- OsDEF7~CAL1~OsAFP1, OsIRT1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Meanwhile, application of sufficient doses of Fe and Cd in solution culture increased RE of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 in roots, whereas expression level of OsHMA3 was decreased
- OsDEF7~CAL1~OsAFP1, OsIRT1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, This may be concluded that the Cd increases expression of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 but decreases OsHMA3 expression in rice roots, which resulted in increased Cd uptake in hydroponically grown rice
- OsIRT1, OsNAAT1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Fe, Mn, and Cd transporters such as CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, OsHMA3, and OsNAAT1 regulate uptake of Cd in rice
- OsIRT1, OsNAAT1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Meanwhile, application of sufficient doses of Fe and Cd in solution culture increased RE of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 in roots, whereas expression level of OsHMA3 was decreased
- OsIRT1, OsNAAT1, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, This may be concluded that the Cd increases expression of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 but decreases OsHMA3 expression in rice roots, which resulted in increased Cd uptake in hydroponically grown rice
- OsIRT1, qCdT7~OsHMA3, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Fe, Mn, and Cd transporters such as CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, OsHMA3, and OsNAAT1 regulate uptake of Cd in rice
- OsIRT1, qCdT7~OsHMA3, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, Meanwhile, application of sufficient doses of Fe and Cd in solution culture increased RE of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 in roots, whereas expression level of OsHMA3 was decreased
- OsIRT1, qCdT7~OsHMA3, Effects of Fe and Mn cations on Cd uptake by rice plant in hydroponic culture experiment, This may be concluded that the Cd increases expression of CAL1, OsNRAMP5, OsNRAMP1, OsIRT1, and OsNAAT1 but decreases OsHMA3 expression in rice roots, which resulted in increased Cd uptake in hydroponically grown rice
- OsIRT1, OsNRAMP1, Melatonin reduces cadmium accumulation via mediating the nitric oxide accumulation and increasing the cell wall fixation capacity of cadmium in rice., Furthermore, MT applied exogenously down-regulated the transcription level of Natural Resistance-Associated Macrophage Protein 1 (OsNRAMP1), OsNRAMP5, a major facilitator superfamily gene (OsCd1), and IRON-REGULATED TRANSPORTER 1 (OsIRT1), all of which were responsible for Cd intake, thus less Cd was entered into roots
- OsIRT1, OsNRAMP5, Melatonin reduces cadmium accumulation via mediating the nitric oxide accumulation and increasing the cell wall fixation capacity of cadmium in rice., Furthermore, MT applied exogenously down-regulated the transcription level of Natural Resistance-Associated Macrophage Protein 1 (OsNRAMP1), OsNRAMP5, a major facilitator superfamily gene (OsCd1), and IRON-REGULATED TRANSPORTER 1 (OsIRT1), all of which were responsible for Cd intake, thus less Cd was entered into roots
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