- Information
- Symbol: DST,WL1,HST1
- MSU: LOC_Os03g57240
- RAPdb: Os03g0786400
- Publication
- The SNAC1-targeted gene OsSRO1c modulates stomatal closure and oxidative stress tolerance by regulating hydrogen peroxide in rice, 2013, J Exp Bot.
- A previously unknown zinc finger protein, DST, regulates drought and salt tolerance in rice via stomatal aperture control, 2009, Genes Dev.
- Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression, 2013, Proc Natl Acad Sci U S A.
- Plasma membrane receptor-like kinase leaf panicle 2 acts downstream of the DROUGHT AND SALT TOLERANCE transcription factor to regulate drought sensitivity in rice., 2014, J Exp Bot.
- Overexpression of a Chimeric Gene, OsDST-SRDX, Improved Salt Tolerance of Perennial Ryegrass., 2016, Sci Rep.
- Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., 2022, J Integr Plant Biol.
- The APC/CTAD1-WIDE LEAF 1-NARROW LEAF 1 pathway controls leaf width in rice., 2022, Plant Cell.
- Genbank accession number
- Key message
- Here, we clone and characterize DST (drought and salt tolerance)-a previously unknown zinc finger transcription factor that negatively regulates stomatal closure by direct modulation of genes related to H(2)O(2) homeostasis-and identify a novel pathway for the signal transduction of DST-mediated H(2)O(2)-induced stomatal closure
- Loss of DST function increases stomatal closure and reduces stomatal density, consequently resulting in enhanced drought and salt tolerance in rice
- A previously unknown zinc finger protein, DST, regulates drought and salt tolerance in rice via stomatal aperture control
- We identify that DST(reg1), a semidominant allele of the DST gene, perturbs DST-directed regulation of OsCKX2 expression and elevates CK levels in the reproductive SAM, leading to increased meristem activity, enhanced panicle branching, and a consequent increase of grain number
- Here, we report that the zinc finger transcription factor DROUGHT AND SALT TOLERANCE (DST) directly regulates OsCKX2 expression in the reproductive meristem
- Our study reveals that, as a unique regulator of reproductive meristem activity, DST may be explored to facilitate the genetic enhancement of grain production in rice and other small grain cereals
- Importantly, the DST(reg1) allele provides an approach to pyramid the Gn1a-dependent and Gn1a-independent effects on grain production
- Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression
- DST-directed expression of OsCKX2 regulates CK accumulation in the SAM and, therefore, controls the number of the reproductive organs
- The results suggest that OsSRO1c has dual roles in drought and oxidative stress tolerance of rice by promoting stomatal closure and H(2)O(2) accumulation through a novel pathway involving regulators SNAC1 and DST
- Expression of DST, a reported zinc finger gene negatively regulating H(2)O(2)-induced stomatal closure, and the activity of H(2)O(2)-scavenging related enzymes were significantly suppressed, and H(2)O(2) in guard cells was accumulated in the overexpression lines
- Plasma membrane receptor-like kinase leaf panicle 2 acts downstream of the DROUGHT AND SALT TOLERANCE transcription factor to regulate drought sensitivity in rice
- Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice.
- Phenotypic analyses revealed that OsMED25-RNAi and the osmed25 mutant plants exhibited enlarged panicles, with enhanced branching and spikelet number, similar to the dst mutant
- Thus, OsMED25 was involved in the communication between DST and Pol II general transcriptional machinery to regulate spikelet number
- Interestingly, we found that WL1 negatively regulated the expression of a narrow leaf gene, NARROW LEAF 1 (NAL1), by recruiting the co-repressor TOPLESS-RELATED PROTEIN and directly binding to the NAL1 regulatory region to inhibit its expression by reducing the chromatin histone acetylation
- WL1 encodes a Cys-2/His-2-type (C2H2) zinc finger protein that interacts with Tillering and Dwarf 1 (TAD1), a co-activator of the anaphase-promoting complex/cyclosome (APC/C) (a multi-subunit E3 ligase)
- Connection
- DST~WL1~HST1, OsSRO1c~BOC1, The SNAC1-targeted gene OsSRO1c modulates stomatal closure and oxidative stress tolerance by regulating hydrogen peroxide in rice, The results suggest that OsSRO1c has dual roles in drought and oxidative stress tolerance of rice by promoting stomatal closure and H(2)O(2) accumulation through a novel pathway involving regulators SNAC1 and DST
- DST~WL1~HST1, OsNAC19~SNAC1~OsNAC9, The SNAC1-targeted gene OsSRO1c modulates stomatal closure and oxidative stress tolerance by regulating hydrogen peroxide in rice, The results suggest that OsSRO1c has dual roles in drought and oxidative stress tolerance of rice by promoting stomatal closure and H(2)O(2) accumulation through a novel pathway involving regulators SNAC1 and DST
- DST~WL1~HST1, Gn1a~OsCKX2, Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression, Here, we report that the zinc finger transcription factor DROUGHT AND SALT TOLERANCE (DST) directly regulates OsCKX2 expression in the reproductive meristem
- DST~WL1~HST1, Gn1a~OsCKX2, Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression, DST-directed expression of OsCKX2 regulates CK accumulation in the SAM and, therefore, controls the number of the reproductive organs
- DST~WL1~HST1, Gn1a~OsCKX2, Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression, We identify that DST(reg1), a semidominant allele of the DST gene, perturbs DST-directed regulation of OsCKX2 expression and elevates CK levels in the reproductive SAM, leading to increased meristem activity, enhanced panicle branching, and a consequent increase of grain number
- DST~WL1~HST1, Gn1a~OsCKX2, Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression, Importantly, the DST(reg1) allele provides an approach to pyramid the Gn1a-dependent and Gn1a-independent effects on grain production
- DST~WL1~HST1, Gn1a~OsCKX2, Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression, Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression
- DST~WL1~HST1, LP2, Plasma membrane receptor-like kinase leaf panicle 2 acts downstream of the DROUGHT AND SALT TOLERANCE transcription factor to regulate drought sensitivity in rice, Further investigation revealed that transcription of LP2 was directly regulated by the zinc finger transcription factor DROUGHT AND SALT TOLERANCE (DST)
- DST~WL1~HST1, LP2, Plasma membrane receptor-like kinase leaf panicle 2 acts downstream of the DROUGHT AND SALT TOLERANCE transcription factor to regulate drought sensitivity in rice., Further investigation revealed that transcription of LP2 was directly regulated by the zinc finger transcription factor DROUGHT AND SALT TOLERANCE (DST)
- DST~WL1~HST1, LP2, Plasma membrane receptor-like kinase leaf panicle 2 acts downstream of the DROUGHT AND SALT TOLERANCE transcription factor to regulate drought sensitivity in rice., Thus, the findings provided evidence that the LRR-RLK LP2, transcriptionally regulated by the drought-related transcription factor DST, served as a negative regulator in drought response
- DCA1, DST~WL1~HST1, DCA1 Acts as a Transcriptional Co-activator of DST and Contributes to Drought and Salt Tolerance in Rice., DCA1 Acts as a Transcriptional Co-activator of DST and Contributes to Drought and Salt Tolerance in Rice.
- DCA1, DST~WL1~HST1, DCA1 Acts as a Transcriptional Co-activator of DST and Contributes to Drought and Salt Tolerance in Rice., In the present study, we demonstrated that DST Co-activator 1 (DCA1), a previously unknown CHY zinc finger protein, acts as an interacting co-activator of DST
- DCA1, DST~WL1~HST1, DCA1 Acts as a Transcriptional Co-activator of DST and Contributes to Drought and Salt Tolerance in Rice., DST was found to physically interact with itself and to form a heterologous tetramer with DCA1
- DCA1, DST~WL1~HST1, DCA1 Acts as a Transcriptional Co-activator of DST and Contributes to Drought and Salt Tolerance in Rice., Moreover, due to the evolutionary and functional conservation of DCA1 and DST in plants, engineering of this pathway has the potential to improve tolerance to abiotic stress in other important crop species
- DST~WL1~HST1, OsER1, ERECTA1 Acts Upstream of the OsMKKK10-OsMKK4-OsMPK6 Cascade to Control Spikelet Number by Regulating Cytokinin Metabolism in Rice , Furthermore, overexpression of either DST or OsCKX2 rescued the spikelet number phenotype of the oser1, osmkkk10, osmkk4, and osmpk6 mutants, suggesting that the DST-OsCKX2 module genetically functions downstream of the OsER1-OsMKKK10-OsMKK4-OsMPK6 pathway
- DST~WL1~HST1, YDA1~SMG2~OsMKKK10, ERECTA1 Acts Upstream of the OsMKKK10-OsMKK4-OsMPK6 Cascade to Control Spikelet Number by Regulating Cytokinin Metabolism in Rice , Furthermore, overexpression of either DST or OsCKX2 rescued the spikelet number phenotype of the oser1, osmkkk10, osmkk4, and osmpk6 mutants, suggesting that the DST-OsCKX2 module genetically functions downstream of the OsER1-OsMKKK10-OsMKK4-OsMPK6 pathway
- DST~WL1~HST1, OsMKK4~LARGE11, ERECTA1 Acts Upstream of the OsMKKK10-OsMKK4-OsMPK6 Cascade to Control Spikelet Number by Regulating Cytokinin Metabolism in Rice , Furthermore, overexpression of either DST or OsCKX2 rescued the spikelet number phenotype of the oser1, osmkkk10, osmkk4, and osmpk6 mutants, suggesting that the DST-OsCKX2 module genetically functions downstream of the OsER1-OsMKKK10-OsMKK4-OsMPK6 pathway
- DST~WL1~HST1, OsMPK6~OsMPK4, ERECTA1 Acts Upstream of the OsMKKK10-OsMKK4-OsMPK6 Cascade to Control Spikelet Number by Regulating Cytokinin Metabolism in Rice , OsMPK6 directly interacts with and phosphorylates the zinc finger transcription factor DST to enhance its transcriptional activation of CYTOKININ OXIDASE2 (OsCKX2), indicating that the OsER1-OsMKKK10-OsMKK4-OsMPK6 pathway shapes panicle morphology by regulating cytokinin metabolism
- DST~WL1~HST1, OsMPK6~OsMPK4, ERECTA1 Acts Upstream of the OsMKKK10-OsMKK4-OsMPK6 Cascade to Control Spikelet Number by Regulating Cytokinin Metabolism in Rice , Furthermore, overexpression of either DST or OsCKX2 rescued the spikelet number phenotype of the oser1, osmkkk10, osmkk4, and osmpk6 mutants, suggesting that the DST-OsCKX2 module genetically functions downstream of the OsER1-OsMKKK10-OsMKK4-OsMPK6 pathway
- DST~WL1~HST1, HDA704, Rice histone deacetylase HDA704 positively regulates drought and salt tolerance by controlling stomatal aperture and density., HDA704 negatively regulates stomatal aperture and density, repressing the transcription of DST and ABIL2 by histone deacetylation modification
- DST~WL1~HST1, HDA704, Rice histone deacetylase HDA704 positively regulates drought and salt tolerance by controlling stomatal aperture and density., Our results showed that HDA704 directly binds to DST and ABIL2, repressing their expression via histone deacetylation modification
- DST~WL1~HST1, HDA704, Rice histone deacetylase HDA704 positively regulates drought and salt tolerance by controlling stomatal aperture and density., Collectively, these findings reveal that HDA704 positively regulates drought and salt tolerance by repressing the expression of DST and ABIL2
- DST~WL1~HST1, OsMED25, Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., Here, we demonstrate that DST-interacting protein 1 (DIP1), known as Mediator subunit OsMED25, acts as an interacting coactivator of DST
- DST~WL1~HST1, OsMED25, Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., Phenotypic analyses revealed that OsMED25-RNAi and the osmed25 mutant plants exhibited enlarged panicles, with enhanced branching and spikelet number, similar to the dst mutant
- DST~WL1~HST1, OsMED25, Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., Further biochemical analysis showed that OsMED25 physically interacts with DST at the promoter region of OsCKX2, and then recruits RNA polymerase II (Pol II) to activate OsCKX2 transcription
- DST~WL1~HST1, OsMED25, Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., Thus, OsMED25 was involved in the communication between DST and Pol II general transcriptional machinery to regulate spikelet number
- DST~WL1~HST1, Gn1a~OsCKX2, Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., In rice, the zinc finger transcription factor DROUGHT AND SALT TOLERANCE (DST) controls grain number by directly regulating cytokinin oxidase/dehydrogenase 2 (OsCKX2) expression
- DST~WL1~HST1, Gn1a~OsCKX2, Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., Although specific upstream regulators of the DST-OsCKX2 module have been identified, the mechanism employed by DST to regulate the expression of OsCKX2 remains unclear
- DST~WL1~HST1, Gn1a~OsCKX2, Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice., Further biochemical analysis showed that OsMED25 physically interacts with DST at the promoter region of OsCKX2, and then recruits RNA polymerase II (Pol II) to activate OsCKX2 transcription
- DST~WL1~HST1, NAL1~qFLW4~LVPA4, The APC/CTAD1-WIDE LEAF 1-NARROW LEAF 1 pathway controls leaf width in rice., Interestingly, we found that WL1 negatively regulated the expression of a narrow leaf gene, NARROW LEAF 1 (NAL1), by recruiting the co-repressor TOPLESS-RELATED PROTEIN and directly binding to the NAL1 regulatory region to inhibit its expression by reducing the chromatin histone acetylation
- DST~WL1~HST1, NAL1~qFLW4~LVPA4, The APC/CTAD1-WIDE LEAF 1-NARROW LEAF 1 pathway controls leaf width in rice., Furthermore, biochemical and genetic analyses revealed that TAD1, WL1, and NAL1 operated in a common pathway to control the leaf width
Prev Next