OsPELOTA,LML1,Ospelo

• Symbol: OsPELOTA,LML1,Ospelo
• MSU: LOC_Os04g56480
• RAPdb: Os04g0659900

• A substitution mutation in OsPELOTA confers bacterial blight resistance by activating the salicylic acid pathway., 2017, J Integr Plant Biol.
• LML1, Encoding a Conserved Eukaryotic Release Factor 1 Protein, Regulates Cell Death and Pathogen Resistance by Forming a Conserved Complex with SPL33 in Rice., 2018, Plant Cell Physiol.
• A Pelota-like gene regulates root development and defence responses in rice., 2018, Ann Bot.

Genbank accession number

• A substitution mutation in OsPELOTA confers bacterial blight resistance by activating the salicylic acid pathway.
• Here, we report the map-based cloning of the causal gene OsPELOTA (originally termed splHM47 )
• LML1 is expressed in all types of leaf cells, and encodes a novel eukaryotic release factor 1 (eRF1) protein located in the endoplasmic reticulum (ER)
• LML1 can partially rescue the growth delay phenotype of the LML1 yeast ortholog mutant, dom34
• Both lml1 and mutants of AtLML1 (the LML1 Arabidopsis ortholog) exhibited a growth delay phenotype as dom34
• The lml1 mutant exhibited abnormal cell death and resistance to both bacterial blight and rice blast
• The Ospelo mutant showed defects in root system development and spotted leaves at early seedling stages
• These results demonstrate that OsPelo positively regulates root development while its loss of function enhances pathogen resistance by pre-activation of defence responses in rice
• Defence responses were induced in the Ospelo mutant, as shown by enhanced resistance to the bacterial pathogen Xanthomonas oryzae pv
• Detailed analysis showed that activation of a number of innate immunity-related genes might be responsible for the enhanced disease resistance in the Ospelo mutant
• OsPelo was found to be expressed in various tissues throughout the plant, and the protein was located in mitochondria
• In addition, whole-genome transcriptome analysis showed that OsPelo was significantly associated with a number of biological processes, including translation, metabolism and biotic stress response

• LMM5.1~SPL33, OsPELOTA~LML1~Ospelo, LML1, Encoding a Conserved Eukaryotic Release Factor 1 Protein, Regulates Cell Death and Pathogen Resistance by Forming a Conserved Complex with SPL33 in Rice., LML1, Encoding a Conserved Eukaryotic Release Factor 1 Protein, Regulates Cell Death and Pathogen Resistance by Forming a Conserved Complex with SPL33 in Rice.