- Information
- Symbol: OsMKP1,GSN1,LARGE8,GLA1
- MSU: LOC_Os05g02500
- RAPdb: Os05g0115800
- Publication
- A calmodulin-binding mitogen-activated protein kinase phosphatase is induced by wounding and regulates the activities of stress-related mitogen-activated protein kinases in rice, 2007, Plant Cell Physiol.
- GRAIN SIZE AND NUMBER1 Negatively Regulates the OsMKKK10-OsMKK4-OsMPK6 Cascade to Coordinate the Trade-off between Grain Number per Panicle and Grain Size in Rice., 2018, Plant Cell.
- A Mitogen-Activated Protein Kinase Phosphatase influences grain size and weight in rice., 2018, Plant J.
- GRAIN LENGTH AND AWN 1 negatively regulates grain size in rice., 2018, J Integr Plant Biol.
- OrMKK3 Influences Morphology and Grain Size in Rice, 2021, J Plant Biol.
- An MKP-MAPK protein phosphorylation cascade controls vascular immunity in plants., 2022, Sci Adv.
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Genbank accession number
- Key message
- Unlike the Arabidopsis atmkp1 loss-of-function mutant, which shows no abnormal phenotype without stimuli, osmkp1 showed a semi-dwarf phenotype
- Exogenous supply of neither gibberellin nor brassinosteroid complemented the semi-dwarf phenotype of osmkp1
- We confirmed that GSN1 is a negative regulator of the OsMKKK10-OsMKK4-OsMPK6 cascade that determines panicle architecture
- Reduced expression of GSN1 resulted in larger and fewer grains, whereas increased expression resulted in more grains but reduced grain size
- GSN1 encodes the mitogen-activated protein kinase phosphatase OsMKP1, a dual-specificity phosphatase of unknown function
- GSN1 directly interacts with and inactivates the mitogen-activated protein kinase OsMPK6 via dephosphorylation
- Consistent with this finding, the suppression of mitogen-activated protein kinase genes OsMPK6, OsMKK4, and OsMKKK10 separately resulted in denser panicles and smaller grains, which rescued the mutant gsn1 phenotypes
- LARGE8 encodes the mitogen-activated protein kinase phosphatase1 (OsMKP1)
- Overexpression of GLA1 caused a decrease in grain length, and the GLA1 protein interacted with OsMAPK6
- These results suggest that GLA1 may serve as a negative regulator of the OsMAPKK4-OsMAPK6 cascade, controlling grain size via the dephosphorylation of OsMAPK6
- The gla1 mutation was mapped to a single-nucleotide polymorphism in a gene encoding a cytoplasmically-localized mitogen-activated protein kinase (MAPK) phosphatase
- Connection
- OsMKP1~GSN1~LARGE8~GLA1, OsMPK6~OsMPK4, A calmodulin-binding mitogen-activated protein kinase phosphatase is induced by wounding and regulates the activities of stress-related mitogen-activated protein kinases in rice, Activities of two stress-responsive MAPKs, OsMPK3 and OsMPK6, in osmkp1 were higher than those in the wild type both before and after wounding
- OsMKK4~LARGE11, OsMKP1~GSN1~LARGE8~GLA1, GRAIN SIZE AND NUMBER1 Negatively Regulates the OsMKKK10-OsMKK4-OsMPK6 Cascade to Coordinate the Trade-off between Grain Number per Panicle and Grain Size in Rice., Consistent with this finding, the suppression of mitogen-activated protein kinase genes OsMPK6, OsMKK4, and OsMKKK10 separately resulted in denser panicles and smaller grains, which rescued the mutant gsn1 phenotypes
- OsMKP1~GSN1~LARGE8~GLA1, OsMPK6~OsMPK4, GRAIN SIZE AND NUMBER1 Negatively Regulates the OsMKKK10-OsMKK4-OsMPK6 Cascade to Coordinate the Trade-off between Grain Number per Panicle and Grain Size in Rice., GSN1 directly interacts with and inactivates the mitogen-activated protein kinase OsMPK6 via dephosphorylation
- OsMKP1~GSN1~LARGE8~GLA1, OsMPK6~OsMPK4, GRAIN SIZE AND NUMBER1 Negatively Regulates the OsMKKK10-OsMKK4-OsMPK6 Cascade to Coordinate the Trade-off between Grain Number per Panicle and Grain Size in Rice., Consistent with this finding, the suppression of mitogen-activated protein kinase genes OsMPK6, OsMKK4, and OsMKKK10 separately resulted in denser panicles and smaller grains, which rescued the mutant gsn1 phenotypes
- OsMKP1~GSN1~LARGE8~GLA1, OsMPK1~OsMAPK6~OsSIPK, GRAIN LENGTH AND AWN 1 negatively regulates grain size in rice., Overexpression of GLA1 caused a decrease in grain length, and the GLA1 protein interacted with OsMAPK6
- OsMKP1~GSN1~LARGE8~GLA1, OsMPK1~OsMAPK6~OsSIPK, GRAIN LENGTH AND AWN 1 negatively regulates grain size in rice., These results suggest that GLA1 may serve as a negative regulator of the OsMAPKK4-OsMAPK6 cascade, controlling grain size via the dephosphorylation of OsMAPK6
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