APIP6

• Symbol: APIP6
• MSU: LOC_Os05g06270
• RAPdb: Os05g0154600

• The Magnaporthe oryzae effector AvrPiz-t targets the RING E3 ubiquitin ligase APIP6 to suppress pathogen-associated molecular pattern-triggered immunity in rice, 2012, Plant Cell.

Genbank accession number

• Silencing of APIP6 in transgenic rice leads to a significant reduction of flg22-induced ROS generation, suppression of defense-related gene expression, and enhanced susceptibility of rice plants to M
• The Magnaporthe oryzae effector AvrPiz-t targets the RING E3 ubiquitin ligase APIP6 to suppress pathogen-associated molecular pattern-triggered immunity in rice

• APIP6, OsEF3~OsELF3-2~OsELF3.2, OsELF3-2, an ortholog of Arabidopsis ELF3, interacts with the E3 ligase APIP6 and negatively regulates immunity against Magnaporthe oryzae in rice, OsELF3-2 interacts with APIP6 and negatively regulates basal resistance against Magnaporthe oryzae.
• APIP12, APIP6, The Nup98 Homolog APIP12 Targeted by the Effector AvrPiz-t is Involved in Rice Basal Resistance Against Magnaporthe oryzae., APIP12 significantly bound to AvrPiz-t and APIP6 in its middle portion and N-terminus, respectively, in yeast two-hybrid assay
• APIP12, APIP6, The Nup98 Homolog APIP12 Targeted by the Effector AvrPiz-t is Involved in Rice Basal Resistance Against Magnaporthe oryzae., Glutathione S-transferase (GST) pull-down assay further verified the interactions of APIP12 with AvrPiz-t and APIP6
• APIP6, OsUBC26, Rice ubiquitin-conjugating enzyme OsUBC26 is essential for immunity to the blast fungus Magnaporthe oryzae, Moreover, OsUBC26 working with APIP6 ubiquitinateds AvrPiz-t, an avirulence effector of M
• APIP6, OsUBC26, Rice ubiquitin-conjugating enzyme OsUBC26 is essential for immunity to the blast fungus Magnaporthe oryzae, In summary, OsUBC26 plays important roles in rice disease resistance by regulating WRKY45 expression and working with E3 ligases such as APIP6 to counteract the effector protein AvrPiz-t from M
• APIP6, UCIP2, Rice ubiquitin-conjugating enzyme OsUBC26 is essential for immunity to the blast fungus Magnaporthe oryzae, Yeast two-hybrid screening using UCIP2 as bait revealed that APIP6 is a binding partner of UCIP2
• APIP6, OsCATC~NOE1~OsCAT3, Rice catalase OsCATC is degraded by E3 ligase APIP6 to negatively regulate immunity, Rice catalase OsCATC is degraded by E3 ligase APIP6 to negatively regulate immunity