TGW6,OsTGW6

2015-01-20 | Categories genes  | Tags yield  grain length  grain  iaa  grain weight  auxin  development  pollen  grain size  pollen development  IAA  breeding 

• Information
  • Symbol: TGW6,OsTGW6
  • MSU: LOC_Os06g41850
  • RAPdb: Os06g0623700
• Publication
  • Loss of function of the IAA-glucose hydrolase gene TGW6 enhances rice grain weight and increases yield, 2013, Nat Genet.
  • Bin-based genome-wide association studies reveal superior alleles for improvement of appearance quality using a 4-way MAGIC population in rice, 2020, J Adv Res.
  • Reinvestigation of THOUSAND-GRAIN WEIGHT 6 grain weight genes in wheat and rice indicates a role in pollen development rather than regulation of auxin content in grains, 2021, Theor Appl Genet.
  • Expression, purification and crystallization of TGW6, which limits grain weight in rice., 2021, Protein Expr Purif.
• Genbank accession number
  • AB513135
• Key message
  • Our findings suggest that TGW6 may be useful for further improvements in yield characteristics in most cultivars
  • Loss of function of the IAA-glucose hydrolase gene TGW6 enhances rice grain weight and increases yield
  • In sink organs, the Nipponbare tgw6 allele affects the timing of the transition from the syncytial to the cellular phase by controlling IAA supply and limiting cell number and grain length
  • Here, we report the cloning and functional analysis of THOUSAND-GRAIN WEIGHT 6 (TGW6), a gene from the Indian landrace rice Kasalath
  • TGW6 encodes a novel protein with indole-3-acetic acid (IAA)-glucose hydrolase activity
  • Phylogenetic and expression analyses of grain weight genes TaTGW6 and OsTGW6 and investigation of substrate availability indicate TGW6 does not regulate auxin content of grains but may affect pollen development
  • This evidence, combined with our observation that developing wheat grains have undetectable levels of ester IAA in comparison to free IAA and do not express an IAA-glucose synthase suggests that TaTGW6 and OsTGW6 do not regulate grain size via the hydrolysis of IAA-glucose
  • However, a critical comparison of data on TaTGW6 and OsTGW6 with other reports on IAA synthesis in cereal grains requires that this hypothesis be reinvestigated
  • The 1-bp deletion allele of tgw6 cloned from the Indian landrace rice cultivar Kasalath, which has lost function, enhances both grain size and yield
  • TGW6 has been utilized as a target for breeding and genome editing to increase the yield of rice
• Connection

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