- Information
- Symbol: OsHKT2;1,OsHKT1
- MSU: LOC_Os06g48810
- RAPdb: Os06g0701700
- Publication
- Rice OsHKT2;1 transporter mediates large Na+ influx component into K+ -starved roots for growth, 2007, EMBO J.
- Expressions of OsHKT1, OsHKT2, and OsVHA are differentially regulated under NaCl stress in salt-sensitive and salt-tolerant rice Oryza sativa L. cultivars, 2006, J Exp Bot.
- Sodium transport and HKT transporters: the rice model, 2003, The Plant Journal.
- HKT2;2/1, a K+-permeable transporter identified in a salt-tolerant rice cultivar through surveys of natural genetic polymorphism, 2012, Plant J.
- Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells, 2010, Plant Physiol.
- OsHKT2;2/1-mediated Na+ influx over K+ uptake in roots potentially increases toxic Na+ accumulation in a salt-tolerant landrace of rice Nona Bokra upon salinity stress., 2015, J Plant Res.
- A role for the OsHKT 2;1 sodium transporter in potassium use efficiency in rice., 2019, J Exp Bot.
- Expression levels of the Na+/K+ transporter OsHKT2;1 and vacuolar Na+/H+ exchanger OsNHX1, Na enrichment, maintaining the photosynthetic abilities and growth performances of indica rice seedlings under salt stress., 2020, Physiol Mol Biol Plants.
- Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis, 2020, EMBO J.
- CC-type glutaredoxin, OsGrx_C7 plays a crucial role in enhancing protection against salt stress in rice, 2021, J Biotechnol.
- OsWRKY28 positively regulates salinity tolerance by directly activating OsDREB1B expression in rice., 2022, Plant Cell Rep.
- Natural variations of chlorophyll fluorescence and ion transporter genes influenced the differential response of japonica rice germplasm with different salt tolerances., 2023, Front Plant Sci.
- Genbank accession number
- Key message
- No-OsHKT2;2/1 is essentially expressed in roots and displays a significant level of expression at high Na(+) concentrations, in contrast to OsHKT2;1
- The OsHKT2;1 (previously named OsHKT1) transporter from rice functions as a relatively Na+-selective transporter in heterologous expression systems, but the in vivo function of OsHKT2;1 remains unknown
- These analyses demonstrate that Na+ can enhance growth of rice under K+ starvation conditions, and that OsHKT2;1 is the central transporter for nutritional Na+ uptake into K+-starved rice roots
- Rice OsHKT2;1 transporter mediates large Na+ influx component into K+ -starved roots for growth
- In addition, the presence of external K(+) and Ca(2+) down-regulated OsHKT2;1-mediated Na(+) influx in two plant systems, Bright-Yellow 2 cells and intact rice roots, and also in Xenopus oocytes
- In roots, the expressions were much lower than in shoots, except for OsHKT4 and OsHKT1 in K+-starved plants
- We propose that OsHKT transporters are involved in Na+ movements in rice, and that OsHKT1 specifically mediates Na+ uptake in rice roots when the plants are K+ deficient
- Yeast expressions of OsHKT1 and OsHKT4 proved that they are Na+ transporters of high and low affinity, respectively, which are sensitive to K+ and Ba2+
- Parallel experiments of K+ and Na+ uptake in yeast expressing the wheat or rice HKT1 transporters proved that they were very different; TaHKT1 transported K+ and Na+, and OsHKT1 only Na+
- Upon NaCl stress, the OsHKT1 transcript was significantly down-regulated in salt-tolerant cv
- Pokkali regulates the expression of OsHKT1, OsHKT2, and OsVHA differently from how the salt-sensitive cv
- Expressions of OsHKT1, OsHKT2, and OsVHA are differentially regulated under NaCl stress in salt-sensitive and salt-tolerant rice (Oryza sativa L.) cultivars
- OsHKT2;1 was mainly expressed in the cortex and endodermis of roots
- (22)Na+ tracer influx experiments revealed that Na+ influx into oshkt2;1-null roots was dramatically reduced compared with wild-type plants
- Therefore, here we analyze two highly homologous rice (Oryza sativa) HKT transporters in plant cells, OsHKT2;1 and OsHKT2;2, that show differential K(+) permeabilities in heterologous systems
- Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells
- We have investigated OsHKT2;1 natural variation in a collection of 49 cultivars with different levels of salt tolerance and geographical origins
- The OsHKT1, OsHKT2, and OsVHA transporter genes might play important roles in maintaining cytosolic Na(+) homeostasis in rice (Oryza sativa L
- Interestingly, three independent oshkt2;1-null alleles exhibited significantly reduced growth compared with wild-type plants under low Na+ and K+ starvation conditions
- Of these, the sodium transporter gene OsHKT2;1 emerged as a key factor that impacts on KUE based on (i) the correlation between shoot Na+ and KUE, and (ii) higher levels of HKT2;1 expression in high KUE lines
- Expression levels of the Na+/K+ transporter OsHKT2;1 and vacuolar Na+/H+ exchanger OsNHX1, Na enrichment, maintaining the photosynthetic abilities and growth performances of indica rice seedlings under salt stress.
- The aim of this investigation was to determine the OsNHX1 (a vacuolar Na+/H+ exchanger) and OsHKT2;1 (Na+/K+ transporter) regulation by salt stress (200<U+00A0>mM NaCl) in two rice cultivars, i
- Pokkali (15<U+00A0>min after salt stress) due to the higher expression of OsHKT2;1 gene (by 2
- Correspondingly, null mutants of OsHKT2;1 displayed an increased tolerance to salt stress
- Under salt stress treatment, the expression levels of OsbZIP05, OsHKT1;1 and OsDREB1B were significantly lower yet the level of OsHKT2;1 was significantly higher in oswrky28 mutants than those in wide type plants
- Connection
- OsHKT2;1~OsHKT1, OsVHA, Expressions of OsHKT1, OsHKT2, and OsVHA are differentially regulated under NaCl stress in salt-sensitive and salt-tolerant rice Oryza sativa L. cultivars, The OsHKT1, OsHKT2, and OsVHA transporter genes might play important roles in maintaining cytosolic Na(+) homeostasis in rice (Oryza sativa L
- OsHKT2;1~OsHKT1, OsVHA, Expressions of OsHKT1, OsHKT2, and OsVHA are differentially regulated under NaCl stress in salt-sensitive and salt-tolerant rice Oryza sativa L. cultivars, Pokkali regulates the expression of OsHKT1, OsHKT2, and OsVHA differently from how the salt-sensitive cv
- OsHKT2;1~OsHKT1, OsVHA, Expressions of OsHKT1, OsHKT2, and OsVHA are differentially regulated under NaCl stress in salt-sensitive and salt-tolerant rice Oryza sativa L. cultivars, Expressions of OsHKT1, OsHKT2, and OsVHA are differentially regulated under NaCl stress in salt-sensitive and salt-tolerant rice (Oryza sativa L.) cultivars
- HKT2, OsHKT2;1~OsHKT1, Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa, We also isolated two cDNAs homologous to Ni-OsHKT1 from salt-tolerant indica rice, cv Pokkali (Po-OsHKT1, Po-OsHKT2)
- HKT2, OsHKT2;1~OsHKT1, Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa, The predicted amino acid sequence of Ni-OsHKT1 shares 100% identity with Po-OsHKT1 and 91% identity with Po-OsHKT2, and they are 66-67% identical to wheat HKT1
- HKT2, OsHKT2;1~OsHKT1, Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa, We further characterized the ion-transport properties of OsHKT1 and OsHKT2 using an expression system in the heterologous cells, yeast and Xenopus oocytes
- HKT2, OsHKT2;1~OsHKT1, Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa, OsHKT2 was capable of completely rescuing a K+-uptake deficiency mutation in yeast, whereas OsHKT1 was not under K+-limiting conditions
- HKT2, OsHKT2;1~OsHKT1, Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa, When OsHKTs were expressed in Na+-sensitive yeast, OsHKT1 rendered the cells more Na+-sensitive than did OsHKT2 in high NaCl conditions
- HKT2, OsHKT2;1~OsHKT1, Two types of HKT transporters with different properties of Na+ and K+ transport in Oryza sativa, These results suggest that two isoforms of HKT transporters, a Na+ transporter (OsHKT1) and a Na+- and K+-coupled transporter (OsHKT2), may act harmoniously in the salt tolerant indica rice
- OsHKT1;1~OsHKT4, OsHKT2;1~OsHKT1, Sodium transport and HKT transporters: the rice model, Yeast expressions of OsHKT1 and OsHKT4 proved that they are Na+ transporters of high and low affinity, respectively, which are sensitive to K+ and Ba2+
- OsHKT1;1~OsHKT4, OsHKT2;1~OsHKT1, Sodium transport and HKT transporters: the rice model, In roots, the expressions were much lower than in shoots, except for OsHKT4 and OsHKT1 in K+-starved plants
- OsHKT2;1~OsHKT1, OsHKT2;2, HKT2;2/1, a K+-permeable transporter identified in a salt-tolerant rice cultivar through surveys of natural genetic polymorphism, No-OsHKT2;2/1 is essentially expressed in roots and displays a significant level of expression at high Na(+) concentrations, in contrast to OsHKT2;1
- OsHKT2;1~OsHKT1, OsHKT2;2, HKT2;2/1, a K+-permeable transporter identified in a salt-tolerant rice cultivar through surveys of natural genetic polymorphism, Expressed in Xenopus oocytes or in Saccharomyces cerevisiae, No-OsHKT2;2/1 exhibited a strong permeability to Na(+) and K(+), even at high external Na(+) concentrations, like OsHKT2;2, and in contrast to OsHKT2;1
- OsHKT2;1~OsHKT1, OsHKT2;2, Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells, Therefore, here we analyze two highly homologous rice (Oryza sativa) HKT transporters in plant cells, OsHKT2;1 and OsHKT2;2, that show differential K(+) permeabilities in heterologous systems
- OsHKT2;1~OsHKT1, OsHKT2;2, Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells, Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells
- OsEIL2, OsHKT2;1~OsHKT1, MHZ6/OsEIL1 and OsEIL2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice., Furthermore, this negative regulation by MHZ6/OsEIL1 and OsEIL2 in salt tolerance is likely in part attributable to the direct regulation of OsHKT2;1 expression and Na+ uptake in roots
- OsHKT2;1~OsHKT1, OsPEX11, OsPEX11, a Peroxisomal Biogenesis Factor 11, Contributes to Salt Stress Tolerance in Oryza sativa., Furthermore, qPCR data suggested that OsPEX11 acted as a positive regulator of salt tolerance by reinforcing the expression of several well-known rice transporters (OsHKT2;1, OsHKT1;5, OsLti6a, OsLti6b, OsSOS1, OsNHX1, and OsAKT1) involved in Na(+)/K(+) homeostasis in transgenic plants under salinity
- OsHKT2;1~OsHKT1, OsSIRH2-14, A rice RING H2-type E3 ligase, OsSIRH2-14, enhances salinity tolerance via ubiquitin/26S proteasome-mediated degradation of salt-related proteins., Here, we characterized the rice (Oryza sativa) RING H2-type E3 ligase, OsSIRH2-14 (previously named OsRFPH2-14), which plays a positive role in salinity tolerance by regulating salt-related proteins including an HKT-type Na+ transporter (OsHKT2;1)
- OsHKT2;1~OsHKT1, OsSIRH2-14, A rice RING H2-type E3 ligase, OsSIRH2-14, enhances salinity tolerance via ubiquitin/26S proteasome-mediated degradation of salt-related proteins., In vitro pull-down assays and bimolecular fluorescence complementation assays revealed that OsSIRH2-14 interacts with salt-related proteins, including OsHKT2;1
- OsHKT2;1~OsHKT1, OsSIRH2-14, A rice RING H2-type E3 ligase, OsSIRH2-14, enhances salinity tolerance via ubiquitin/26S proteasome-mediated degradation of salt-related proteins., OsSIRH2-14 E3 ligase regulates OsHKT2;1 via the 26S proteasome system under high NaCl concentrations but not under normal conditions
- OsHKT2;1~OsHKT1, OsNHX1, Expression levels of the Na+/K+ transporter OsHKT2;1 and vacuolar Na+/H+ exchanger OsNHX1, Na enrichment, maintaining the photosynthetic abilities and growth performances of indica rice seedlings under salt stress., Expression levels of the Na+/K+ transporter OsHKT2;1 and vacuolar Na+/H+ exchanger OsNHX1, Na enrichment, maintaining the photosynthetic abilities and growth performances of indica rice seedlings under salt stress.
- OsHKT2;1~OsHKT1, OsNHX1, Expression levels of the Na+/K+ transporter OsHKT2;1 and vacuolar Na+/H+ exchanger OsNHX1, Na enrichment, maintaining the photosynthetic abilities and growth performances of indica rice seedlings under salt stress., The aim of this investigation was to determine the OsNHX1 (a vacuolar Na+/H+ exchanger) and OsHKT2;1 (Na+/K+ transporter) regulation by salt stress (200<U+00A0>mM NaCl) in two rice cultivars, i
- HDAC10, OsHKT2;1~OsHKT1, Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis, Immunoprecipitation-mass spectrometry (IP-MS) assays further identified HDAC10 as nuclear interactor of OsPRR73 and co-repressor of OsHKT2;1
- HDAC10, OsHKT2;1~OsHKT1, Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis, Together, our findings reveal that salt-induced OsPRR73 expression confers salt tolerance by recruiting HDAC10 to transcriptionally repress OsHKT2;1, thus reducing cellular Na+ accumulation
- OsCCT11~OsPRR73, OsHKT2;1~OsHKT1, Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis, RNA sequencing and biochemical assays identified OsHKT2;1, encoding a plasma membrane-localized Na+ transporter, as a transcriptional target of OsPRR73 in mediating salt tolerance
- OsCCT11~OsPRR73, OsHKT2;1~OsHKT1, Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis, Immunoprecipitation-mass spectrometry (IP-MS) assays further identified HDAC10 as nuclear interactor of OsPRR73 and co-repressor of OsHKT2;1
- OsCCT11~OsPRR73, OsHKT2;1~OsHKT1, Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis, Consistently, H3K9ac histone marks at OsHKT2;1 promoter regions were significantly reduced in osprr73 mutant
- OsCCT11~OsPRR73, OsHKT2;1~OsHKT1, Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated sodium homeostasis, Together, our findings reveal that salt-induced OsPRR73 expression confers salt tolerance by recruiting HDAC10 to transcriptionally repress OsHKT2;1, thus reducing cellular Na+ accumulation
- OsGrx_C7, OsHKT2;1~OsHKT1, CC-type glutaredoxin, OsGrx_C7 plays a crucial role in enhancing protection against salt stress in rice, Furthermore, expression analysis suggested that OsGrx_C7 acted as positive regulator of salt tolerance by reinforcing the expression of transporters (OsHKT2;1, OsHKT1;5 and OsSOS1) engaged in Na+ homeostasis in overexpressing plants
- OsHKT1;5~SKC1~OsHKT8~OsHK1;5, OsHKT2;1~OsHKT1, CC-type glutaredoxin, OsGrx_C7 plays a crucial role in enhancing protection against salt stress in rice, Furthermore, expression analysis suggested that OsGrx_C7 acted as positive regulator of salt tolerance by reinforcing the expression of transporters (OsHKT2;1, OsHKT1;5 and OsSOS1) engaged in Na+ homeostasis in overexpressing plants
- OsHKT2;1~OsHKT1, OsNHA1~OsSOS1, CC-type glutaredoxin, OsGrx_C7 plays a crucial role in enhancing protection against salt stress in rice, Furthermore, expression analysis suggested that OsGrx_C7 acted as positive regulator of salt tolerance by reinforcing the expression of transporters (OsHKT2;1, OsHKT1;5 and OsSOS1) engaged in Na+ homeostasis in overexpressing plants
- OsHKT2;1~OsHKT1, OsMADS27, Nitrate-responsive OsMADS27 promotes salt tolerance in rice., We demonstrate that OsMADS27 directly binds to the promoters of OsHKT1
- OsbHLH96~OsbHLH044, OsHKT2;1~OsHKT1, Loss-of-function mutations of OsbHLH044 transcription factor lead to salinity sensitivity and a greater chalkiness in rice Oryza sativa L.., The expression levels of genes coding for starch (OsAGPL1, OsSSIIa, OsWx, and OsFLO2) and seed storage proteins (GluA1 and Globulin 1) were significantly decreased, indicating that they synthesize less store starch and proteins, resulting in grain chalkiness in the osbhlh044 (OsHKT1;3, OsHAK7, OsSOS1, OsSOS2, OsNHX2, and OsLEA3 but not OsHKT2;1), and starch-related genes (OsSSIIa, OsWx, and OsFLO2) by binding to the G-boxes of their promoters
- OsHKT2;1~OsHKT1, OsWRKY28, OsWRKY28 positively regulates salinity tolerance by directly activating OsDREB1B expression in rice., Under salt stress treatment, the expression levels of OsbZIP05, OsHKT1;1 and OsDREB1B were significantly lower yet the level of OsHKT2;1 was significantly higher in oswrky28 mutants than those in wide type plants
- OsDREB1B, OsHKT2;1~OsHKT1, OsWRKY28 positively regulates salinity tolerance by directly activating OsDREB1B expression in rice., Under salt stress treatment, the expression levels of OsbZIP05, OsHKT1;1 and OsDREB1B were significantly lower yet the level of OsHKT2;1 was significantly higher in oswrky28 mutants than those in wide type plants
- OSBZ8~OsbZIP05, OsHKT2;1~OsHKT1, OsWRKY28 positively regulates salinity tolerance by directly activating OsDREB1B expression in rice., Under salt stress treatment, the expression levels of OsbZIP05, OsHKT1;1 and OsDREB1B were significantly lower yet the level of OsHKT2;1 was significantly higher in oswrky28 mutants than those in wide type plants
- OsHKT1;1~OsHKT4, OsHKT2;1~OsHKT1, OsWRKY28 positively regulates salinity tolerance by directly activating OsDREB1B expression in rice., Under salt stress treatment, the expression levels of OsbZIP05, OsHKT1;1 and OsDREB1B were significantly lower yet the level of OsHKT2;1 was significantly higher in oswrky28 mutants than those in wide type plants
- OsHKT1;5~SKC1~OsHKT8~OsHK1;5, OsHKT2;1~OsHKT1, Natural variations of chlorophyll fluorescence and ion transporter genes influenced the differential response of japonica rice germplasm with different salt tolerances., The expression characteristics of chlorophyll fluorescence genes (OsABCI7 and OsHCF222) and ion transporter protein genes (OsHKT1;5, OsHKT2;1, OsHAK21, OsAKT2, OsNHX1, and OsSOS1) were analyzed
- OsAKT2, OsHKT2;1~OsHKT1, Natural variations of chlorophyll fluorescence and ion transporter genes influenced the differential response of japonica rice germplasm with different salt tolerances., The expression characteristics of chlorophyll fluorescence genes (OsABCI7 and OsHCF222) and ion transporter protein genes (OsHKT1;5, OsHKT2;1, OsHAK21, OsAKT2, OsNHX1, and OsSOS1) were analyzed
- OsHAK21~qSE3, OsHKT2;1~OsHKT1, Natural variations of chlorophyll fluorescence and ion transporter genes influenced the differential response of japonica rice germplasm with different salt tolerances., The expression characteristics of chlorophyll fluorescence genes (OsABCI7 and OsHCF222) and ion transporter protein genes (OsHKT1;5, OsHKT2;1, OsHAK21, OsAKT2, OsNHX1, and OsSOS1) were analyzed
- OsHCF222, OsHKT2;1~OsHKT1, Natural variations of chlorophyll fluorescence and ion transporter genes influenced the differential response of japonica rice germplasm with different salt tolerances., The expression characteristics of chlorophyll fluorescence genes (OsABCI7 and OsHCF222) and ion transporter protein genes (OsHKT1;5, OsHKT2;1, OsHAK21, OsAKT2, OsNHX1, and OsSOS1) were analyzed
- OsHKT2;1~OsHKT1, OsNHA1~OsSOS1, Natural variations of chlorophyll fluorescence and ion transporter genes influenced the differential response of japonica rice germplasm with different salt tolerances., The expression characteristics of chlorophyll fluorescence genes (OsABCI7 and OsHCF222) and ion transporter protein genes (OsHKT1;5, OsHKT2;1, OsHAK21, OsAKT2, OsNHX1, and OsSOS1) were analyzed
- OsHKT2;1~OsHKT1, OsNHX1, Natural variations of chlorophyll fluorescence and ion transporter genes influenced the differential response of japonica rice germplasm with different salt tolerances., The expression characteristics of chlorophyll fluorescence genes (OsABCI7 and OsHCF222) and ion transporter protein genes (OsHKT1;5, OsHKT2;1, OsHAK21, OsAKT2, OsNHX1, and OsSOS1) were analyzed
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