Ghd7

2015-01-20 | Categories genes  | Tags height  heading date  flower  grain  floral  grain number  domestication  grains per panicle  panicle  panicle size  breeding  adaptability  yield  chloroplast  map-based cloning  transcriptional activator  flowering time  transcription factor  development  abiotic stress  stress  architecture  biotic stress  stress response  flowering  temperature  growth  growth rate  transcriptional regulator 

• Information
  • Symbol: Ghd7
  • MSU: LOC_Os07g15770
  • RAPdb: Os07g0261200
• Publication
  • Genetic interactions involved in the inhibition of heading by heading date QTL, Hd2 in rice under long-day conditions, 2011, Theor Appl Genet.
  • Roles of the Hd5 gene controlling heading date for adaptation to the northern limits of rice cultivation, 2013, Theor Appl Genet.
  • Molecular dissection of the roles of phytochrome in photoperiodic flowering in rice, 2011, Plant Physiol.
  • A gene network for long-day flowering activates RFT1 encoding a mobile flowering signal in rice, 2009, Development.
  • OsMADS50 and OsMADS56 function antagonistically in regulating long day LD-dependent flowering in rice, 2009, Plant Cell Environ.
  • Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering, 2011, Plant J.
  • Evolution and association analysis of Ghd7 in rice, 2012, PLoS One.
  • OsELF3-1, an ortholog of Arabidopsis early flowering 3, regulates rice circadian rhythm and photoperiodic flowering, 2012, PLoS One.
  • Natural variation in OsPRR37 regulates heading date and contributes to rice cultivation at a wide range of latitudes, 2013, Mol Plant.
  • Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice, 2008, Nat Genet.
  • A pair of floral regulators sets critical day length for Hd3a florigen expression in rice, 2010, Nat Genet.
  • Natural variation in Hd17, a homolog of Arabidopsis ELF3 that is involved in rice photoperiodic flowering, 2012, Plant Cell Physiol.
  • DTH8 suppresses flowering in rice, influencing plant height and yield potential simultaneously, 2010, Plant Physiol.
  • Trithorax group protein Oryza sativa Trithorax1 controls flowering time in rice via interaction with early heading date3, 2014, Plant Physiol.
  • Hd16, a gene for casein kinase I, is involved in the control of rice flowering time by modulating the day-length response, 2013, Plant J.
  • Ghd7 is a central regulator for growth, development, adaptation and responses to biotic and abiotic stresses, 2014, Plant physiology.
  • Genetic architecture of natural variation in rice chlorophyll content revealed by genome wide association study., 2015, Mol Plant.
  • Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., 2015, New Phytol.
  • Hd1,a CONSTANS Orthlog in Rice, Functions as an Ehd1 Repressor Through Interaction with Monocot-Specific CCT-Domain Protein Ghd7., 2016, Plant J.
  • Alternative functions of Hd1 in repressing or promoting heading are determined by Ghd7 status under long-day conditions., 2017, Sci Rep.
  • Importance of the Interaction between Heading Date Genes Hd1 and Ghd7 for Controlling Yield Traits in Rice., 2019, Int J Mol Sci.
  • Early heading 7 interacts with DTH8, and regulates flowering time in rice., 2019, Plant Cell Rep.
  • Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., 2019, New Phytol.
  • The architecture of the GhD7 promoter reveals the roles of GhD7 in growth, development and the abiotic stress response in rice., 2019, Comput Biol Chem.
  • Allelic Differentiation at the E1/Ghd7 Locus Has Allowed Expansion of Rice Cultivation Area., 2019, Plants (Basel).
  • Knockouts of a late flowering gene via CRISPR-Cas9 confer early maturity in rice at multiple field locations, 2020, Plant Mol Biol.
  • Genetic effect of a new allele for the flowering time locus Ghd7 in rice, 2020, Breed Sci.
  • Transcriptional and post-transcriptional regulation of heading date in rice, 2020, New Phytol.
  • OsRRM, an RNA-Binding Protein, Modulates Sugar Transport in Rice Oryza sativa L., 2020, Front Plant Sci.
  • High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice, 2021, Plant Cell Physiol.
  • Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., 2022, J Genet Genomics.
  • The amino acid residue E96 orf Ghd8 is crucial for the formation of the flowering repression complex Ghd7-Ghd8-OsHAP5C in rice., 2022, J Integr Plant Biol.
• Genbank accession number
  • EU286800
  • EU286801
  • EU286800
  • EU286801
• Key message
  • Here we show that the quantitative trait locus (QTL) Ghd7, isolated from an elite rice hybrid and encoding a CCT domain protein, has major effects on an array of traits in rice, including number of grains per panicle, plant height and heading date
  • Enhanced expression of Ghd7 under long-day conditions delays heading and increases plant height and panicle size
  • Moreover, OsELF3-1 suppresses a flowering repressor grain number, plant height and heading date 7 (Ghd7) to indirectly accelerate flowering under long-day (LD) conditions
  • Ehd1 and Hd3a can also be down-regulated by the photoperiodic flowering genes Ghd7 and Hd1 (a rice ortholog of CONSTANS)
  • By using near-isogenic lines with functional or deficient alleles of several rice flowering-time genes, we observed significant digenetic interactions between Hd16 and four other flowering-time genes (Ghd7, Hd1, DTH8 and Hd2)
  • These results demonstrate that Hd16 acts as an inhibitor in the rice flowering pathway by enhancing the photoperiod response as a result of the phosphorylation of Ghd7
  • Our results demonstrate that natural variation in Hd17 may change the transcription level of a flowering repressor, Grain number, plant height and heading date 7 (Ghd7), suggesting that Hd17 is part of rice’s photoperiodic flowering pathway
  • On the other hand, under long-day (LD) conditions, flowering is delayed by the repressive function of Hd1 on FT-like genes and by downregulation of Ehd1 by the flowering repressor Ghd7 - a unique pathway in rice
  • Furthermore, Ehd3 ghd7 plants flowered earlier and show higher Ehd1 transcript levels than ehd3 ghd7 plants, suggesting a Ghd7-independent role of Ehd3 in the upregulation of Ehd1
  • We propose that both positive (OsMADS50 and Ehd1) and negative (Hd1, phyB and Ghd7) regulators of RFT1 form a gene network that regulates LD flowering in rice
  • Ghd7 (Grain number, plant height and heading date 7) was acutely induced when phytochrome signals coincided with a photosensitive phase set differently by distinct photoperiods and this induction repressed Ehd1 the next morning
  • However, the Grain number, plant height, and heading date7 (Ghd7) pathway was altered in ostrx1
  • Increased transcription of Ghd7 under LD conditions and reduced transcription of downstream Ehd1 and FT-like genes in the ehd3 mutants suggested that Ehd3 normally functions as an LD downregulator of Ghd7 in floral induction
  • rufipogon) was used to analyze the evolution and association of Ghd7 with plant height, heading date, and yield
  • Meanwhile, the transcription of DTH8 has been proved to be independent of Ghd7 and Hd1, and the natural mutation of this gene caused weak photoperiod sensitivity and shorter plant height
  • Analyses using a rice phytochrome chromophore-deficient mutant, photoperiod sensitivity5, have so far revealed that within this network, phytochromes are required for expression of Grain number, plant height and heading date7 (Ghd7), a floral repressor gene in rice
  • Similarly, in the homozygous Koshihikari genetic background at Ghd7, the difference in heading date caused by different alleles at Hd2 was smaller than in plants homozygous for the Hayamasari Ghd7 allele
  • In addition, QTLs near Hd2, Hd16, and Ghd7, which are involved in inhibition of heading under long-day conditions, function in the same pathway that controls heading date
  • SNP changes between haplotypes indicated that Ghd7 evolved from two distinct ancestral gene pools, and independent domestication processes were detected in indica and japonica varietals respectively
  • Thus, two distinct gating mechanisms–of the floral promoter Ehd1 and the floral repressor Ghd7–could enable manipulation of slight differences in day length to control Hd3a transcription with a critical day-length threshold
  • Transcript levels of OsGI, phytochrome genes, and Early heading date3 (Ehd3), which function upstream of Ghd7, were unchanged in the mutant
  • Moreover, phyB and phyA can affect Ghd7 activity and Early heading date1 (a floral inducer) activity in the network, respectively
  • These associations provide the potential for flexibility of Ghd7 application in rice breeding programs
  • Notably, the japonica varieties harboring nonfunctional alleles of both Ghd7/Hd4 and PRR37/Hd2 flower extremely early under natural long-day conditions, and are adapted to the northernmost regions of rice cultivation, up to 53 degrees N latitude
  • Genetic analysis revealed that the effects of PRR37 and Ghd7 alleles on heading date are additive, and PRR37 down-regulates Hd3a expression to suppress flowering under long-day conditions
  • Thus, Ghd7 has played crucial roles for increasing productivity and adaptability of rice globally
  • Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice
  • The enhanced expression of Ghd7 decreased chlorophyll content, mainly through down-regulating the expression of genes involved in the biosynthesis of chlorophyll and chloroplast
  • We employed a map-based cloning approach to isolate a heading date gene, which coordinated the interaction between Ghd7 and Ghd8 to greatly delay rice heading
  • Map-based cloning demonstrated that the gene largely affecting the interaction between Ghd7 and Ghd8 was Hd1
  • Here, we report biological interactions between Ghd7 and Hd1, which together repress Early heading date 1 (Ehd1), a key floral inducer under non-inductive long-day (LD) conditions
  • These findings imply that Hd1, an evolutionally conserved transcriptional activator, can function as a strong transcriptional repressor within a monocot-specific flowering-time pathway through with Ghd7
  • These findings suggest that Hd1 alone essentially acts as a promoter of heading date, and the protein interaction between Ghd7 and Hd1 determines photoperiod sensitivity and integrated Hd1-mediated and Ehd1-mediated flowering pathways in rice
  • Importance of the Interaction between Heading Date Genes Hd1 and Ghd7 for Controlling Yield Traits in Rice.
  • In this study, influences of interaction between Hd1 and Ghd7 on flowering time and yield traits were analyzed using near isogenic lines derived from a cross between indica rice cultivars ZS97 and MY46
  • Ghd7 is a major regulator of flowering time in rice, which strongly delays flowering under LD
  • We also found that co-expressing OsGI with Ghd7 causes reduced accumulation of Ghd7 protein and partially suppresses the delayed flowering phenotype in the wild type background, suggesting that phytochromes and OsGI play antagonist roles in regulating Ghd7 protein stability and flowering time
  • This study was carried out to explore the transcription factor binding site (TFBS) architecture of the GhD7 promoter to identify the regulatory dynamics of GhD7 transcription
  • In addition to the previously identified 8 cis-elements, 448 novel cis-elements were identified in the GhD7 promoter that provide binding sites for 25 transcription factor families
  • The identified transcription factor families include key transcription factors involved in both development and abiotic stress responses, revealing the regulatory dynamics of GhD7
  • The architecture of the GhD7 promoter reveals the roles of GhD7 in growth, development and the abiotic stress response in rice.
  • GhD7 delays the plant’s flowering under long-day conditions, which ultimately results in increased yield
  • Recent findings indicate that GhD7 also plays a major role in the abiotic stress response; however, the fine regulatory mechanisms controlling Ghd7 expression have yet to be uncovered
  • This study supports the model that GhD7 acts as a central regulator of rice growth, development, and the abiotic stress response
  • OsGhd7 is a functional allele of the Ghd7 gene family; knockouts of OsGhd7 generated by CRISPR-Cas9 significantly accelerated flowering time and the earliness of the flowering time depended on field location
  • Genetic effect of a new allele for the flowering time locus Ghd7 in rice
  • Segregation analysis using an F2 population derived from the cross between Hoshinoyume and Sorachi demonstrated that the Ghd7 locus contributed to extremely early flowering time in Sorachi
  • This Ghd7 allele in Sorachi showed a weak function in terms of delay of flowering time, compared with loss-of-function allele, and a distinct distribution in northern Japan
  • We also revealed that PhyB can control Ghd7 repressor activity as a temperature sensor to inhibit Ehd1, Hd3a, and RFT1 at lower temperatures, likely through a post-transcriptional regulation, despite inductive photoperiod conditions
  • In addition to delayed flowering because of low growth rates, we found that photoperiodic flowering is clearly enhanced by both Hd1 and Ghd7 genes under low-temperature conditions in rice
  • The rising of ambient temperatures in early summer would contribute to inhibition of Ghd7 repressor activity, resulting in the appropriate floral induction of rice in temperate climates
  • A Ghd7 involved transcriptional regulatory network has been established, but its translational regulatory pathway is poorly understood
  • Ghd7 is an important gene involving in photoperiod flowering pathway in rice
  • These findings are helpful to deeply understand the Ghd7 involved photoperiod flowering pathway and promote the elucidation of rice heading
• Connection
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Genetic interactions involved in the inhibition of heading by heading date QTL, Hd2 in rice under long-day conditions, Combinations of several QTLs near Hd1, Hd2, Ghd7, Hd5, and Hd16 were detected under these four conditions
  • Ghd7, Hd1, Genetic interactions involved in the inhibition of heading by heading date QTL, Hd2 in rice under long-day conditions, Combinations of several QTLs near Hd1, Hd2, Ghd7, Hd5, and Hd16 were detected under these four conditions
  • CKI~EL1~Hd16, Ghd7, Genetic interactions involved in the inhibition of heading by heading date QTL, Hd2 in rice under long-day conditions, Combinations of several QTLs near Hd1, Hd2, Ghd7, Hd5, and Hd16 were detected under these four conditions
  • CKI~EL1~Hd16, Ghd7, Genetic interactions involved in the inhibition of heading by heading date QTL, Hd2 in rice under long-day conditions, Analysis of advanced backcross progenies revealed genetic interactions between Hd2 and Hd16 and between Hd2 and Ghd7
  • CKI~EL1~Hd16, Ghd7, Genetic interactions involved in the inhibition of heading by heading date QTL, Hd2 in rice under long-day conditions, In addition, QTLs near Hd2, Hd16, and Ghd7, which are involved in inhibition of heading under long-day conditions, function in the same pathway that controls heading date
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Roles of the Hd5 gene controlling heading date for adaptation to the northern limits of rice cultivation, The loss-of-function Hd5 was then introduced into the rice variety Fanny from France and contributed to its extremely early heading under the presence of functional Ghd7
  • Ghd7, PHYA~OsPhyA, Molecular dissection of the roles of phytochrome in photoperiodic flowering in rice, Our results show that either phyA alone or a genetic combination of phyB and phyC can induce Ghd7 mRNA, whereas phyB alone causes some reduction in levels of Ghd7 mRNA
  • Ghd7, PHYA~OsPhyA, Molecular dissection of the roles of phytochrome in photoperiodic flowering in rice, Moreover, phyB and phyA can affect Ghd7 activity and Early heading date1 (a floral inducer) activity in the network, respectively
  • Ghd7, PHYB~OsphyB, Molecular dissection of the roles of phytochrome in photoperiodic flowering in rice, Our results show that either phyA alone or a genetic combination of phyB and phyC can induce Ghd7 mRNA, whereas phyB alone causes some reduction in levels of Ghd7 mRNA
  • Ghd7, PHYB~OsphyB, Molecular dissection of the roles of phytochrome in photoperiodic flowering in rice, Moreover, phyB and phyA can affect Ghd7 activity and Early heading date1 (a floral inducer) activity in the network, respectively
  • Ghd7, PHYC~OsphyC~LHD3, Molecular dissection of the roles of phytochrome in photoperiodic flowering in rice, Our results show that either phyA alone or a genetic combination of phyB and phyC can induce Ghd7 mRNA, whereas phyB alone causes some reduction in levels of Ghd7 mRNA
  • Ghd7, Hd1, A gene network for long-day flowering activates RFT1 encoding a mobile flowering signal in rice, We propose that both positive (OsMADS50 and Ehd1) and negative (Hd1, phyB and Ghd7) regulators of RFT1 form a gene network that regulates LD flowering in rice
  • Ghd7, PHYB~OsphyB, A gene network for long-day flowering activates RFT1 encoding a mobile flowering signal in rice, We propose that both positive (OsMADS50 and Ehd1) and negative (Hd1, phyB and Ghd7) regulators of RFT1 form a gene network that regulates LD flowering in rice
  • Ehd1, Ghd7, A gene network for long-day flowering activates RFT1 encoding a mobile flowering signal in rice, We propose that both positive (OsMADS50 and Ehd1) and negative (Hd1, phyB and Ghd7) regulators of RFT1 form a gene network that regulates LD flowering in rice
  • Ghd7, OsGI-Hd1-Hd3a~RFT1, A gene network for long-day flowering activates RFT1 encoding a mobile flowering signal in rice, We propose that both positive (OsMADS50 and Ehd1) and negative (Hd1, phyB and Ghd7) regulators of RFT1 form a gene network that regulates LD flowering in rice
  • Ghd7, OsMADS50~OsSOC1~DTH3, A gene network for long-day flowering activates RFT1 encoding a mobile flowering signal in rice, We propose that both positive (OsMADS50 and Ehd1) and negative (Hd1, phyB and Ghd7) regulators of RFT1 form a gene network that regulates LD flowering in rice
  • Ghd7, Hd6~CK2, OsMADS50 and OsMADS56 function antagonistically in regulating long day LD-dependent flowering in rice, On the other hand, mRNA levels of OsGI, Hd1, OsId1, OsDof12, Ghd7, Hd6 and SE5 were unchanged
  • Ghd7, OsDof12~OsCDF1, OsMADS50 and OsMADS56 function antagonistically in regulating long day LD-dependent flowering in rice, On the other hand, mRNA levels of OsGI, Hd1, OsId1, OsDof12, Ghd7, Hd6 and SE5 were unchanged
  • Ghd7, OsGI, OsMADS50 and OsMADS56 function antagonistically in regulating long day LD-dependent flowering in rice, On the other hand, mRNA levels of OsGI, Hd1, OsId1, OsDof12, Ghd7, Hd6 and SE5 were unchanged
  • Ghd7, Hd1, OsMADS50 and OsMADS56 function antagonistically in regulating long day LD-dependent flowering in rice, On the other hand, mRNA levels of OsGI, Hd1, OsId1, OsDof12, Ghd7, Hd6 and SE5 were unchanged
  • Ehd1, Ghd7, Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering, On the other hand, under long-day (LD) conditions, flowering is delayed by the repressive function of Hd1 on FT-like genes and by downregulation of Ehd1 by the flowering repressor Ghd7 - a unique pathway in rice
  • Ehd1, Ghd7, Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering, Increased transcription of Ghd7 under LD conditions and reduced transcription of downstream Ehd1 and FT-like genes in the ehd3 mutants suggested that Ehd3 normally functions as an LD downregulator of Ghd7 in floral induction
  • Ehd1, Ghd7, Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering, Furthermore, Ehd3 ghd7 plants flowered earlier and show higher Ehd1 transcript levels than ehd3 ghd7 plants, suggesting a Ghd7-independent role of Ehd3 in the upregulation of Ehd1
  • Ghd7, Hd1, Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering, On the other hand, under long-day (LD) conditions, flowering is delayed by the repressive function of Hd1 on FT-like genes and by downregulation of Ehd1 by the flowering repressor Ghd7 - a unique pathway in rice
  • Ehd3, Ghd7, Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering, Increased transcription of Ghd7 under LD conditions and reduced transcription of downstream Ehd1 and FT-like genes in the ehd3 mutants suggested that Ehd3 normally functions as an LD downregulator of Ghd7 in floral induction
  • Ehd3, Ghd7, Ehd3, encoding a plant homeodomain finger-containing protein, is a critical promoter of rice flowering, Furthermore, Ehd3 ghd7 plants flowered earlier and show higher Ehd1 transcript levels than ehd3 ghd7 plants, suggesting a Ghd7-independent role of Ehd3 in the upregulation of Ehd1
  • Ghd7, Hd17~Ef7~OsELF3-1~OsELF3.1~OsELF3, OsELF3-1, an ortholog of Arabidopsis early flowering 3, regulates rice circadian rhythm and photoperiodic flowering, Moreover, OsELF3-1 suppresses a flowering repressor grain number, plant height and heading date 7 (Ghd7) to indirectly accelerate flowering under long-day (LD) conditions
  • Ehd1, Ghd7, A pair of floral regulators sets critical day length for Hd3a florigen expression in rice, Ghd7 (Grain number, plant height and heading date 7) was acutely induced when phytochrome signals coincided with a photosensitive phase set differently by distinct photoperiods and this induction repressed Ehd1 the next morning
  • Ehd1, Ghd7, A pair of floral regulators sets critical day length for Hd3a florigen expression in rice, Thus, two distinct gating mechanisms–of the floral promoter Ehd1 and the floral repressor Ghd7–could enable manipulation of slight differences in day length to control Hd3a transcription with a critical day-length threshold
  • Ghd7, Hd3a, A pair of floral regulators sets critical day length for Hd3a florigen expression in rice, Thus, two distinct gating mechanisms–of the floral promoter Ehd1 and the floral repressor Ghd7–could enable manipulation of slight differences in day length to control Hd3a transcription with a critical day-length threshold
  • Ghd7, Hd17~Ef7~OsELF3-1~OsELF3.1~OsELF3, Natural variation in Hd17, a homolog of Arabidopsis ELF3 that is involved in rice photoperiodic flowering, Our results demonstrate that natural variation in Hd17 may change the transcription level of a flowering repressor, Grain number, plant height and heading date 7 (Ghd7), suggesting that Hd17 is part of rice’s photoperiodic flowering pathway
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, DTH8 suppresses flowering in rice, influencing plant height and yield potential simultaneously, Meanwhile, the transcription of DTH8 has been proved to be independent of Ghd7 and Hd1, and the natural mutation of this gene caused weak photoperiod sensitivity and shorter plant height
  • Ehd1, Ghd7, DTH8 suppresses flowering in rice, influencing plant height and yield potential simultaneously, Ehd1 and Hd3a can also be down-regulated by the photoperiodic flowering genes Ghd7 and Hd1 (a rice ortholog of CONSTANS)
  • Ghd7, Hd1, DTH8 suppresses flowering in rice, influencing plant height and yield potential simultaneously, Ehd1 and Hd3a can also be down-regulated by the photoperiodic flowering genes Ghd7 and Hd1 (a rice ortholog of CONSTANS)
  • Ghd7, Hd1, DTH8 suppresses flowering in rice, influencing plant height and yield potential simultaneously, Meanwhile, the transcription of DTH8 has been proved to be independent of Ghd7 and Hd1, and the natural mutation of this gene caused weak photoperiod sensitivity and shorter plant height
  • Ghd7, Hd3a, DTH8 suppresses flowering in rice, influencing plant height and yield potential simultaneously, Ehd1 and Hd3a can also be down-regulated by the photoperiodic flowering genes Ghd7 and Hd1 (a rice ortholog of CONSTANS)
  • Ehd3, Ghd7, Trithorax group protein Oryza sativa Trithorax1 controls flowering time in rice via interaction with early heading date3, Transcript levels of OsGI, phytochrome genes, and Early heading date3 (Ehd3), which function upstream of Ghd7, were unchanged in the mutant
  • Ghd7, OsGI, Trithorax group protein Oryza sativa Trithorax1 controls flowering time in rice via interaction with early heading date3, Transcript levels of OsGI, phytochrome genes, and Early heading date3 (Ehd3), which function upstream of Ghd7, were unchanged in the mutant
  • Ghd7, OsTrx1~SDG723, Trithorax group protein Oryza sativa Trithorax1 controls flowering time in rice via interaction with early heading date3, However, the Grain number, plant height, and heading date7 (Ghd7) pathway was altered in ostrx1
  • Ghd7, OsTrx1~SDG723, Trithorax group protein Oryza sativa Trithorax1 controls flowering time in rice via interaction with early heading date3, Because Trx group proteins form a complex with other proteins to modify the chromatin structure of target genes, we investigated whether OsTrx1 interacts with a previously identified protein that functions upstream of Ghd7
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Hd16, a gene for casein kinase I, is involved in the control of rice flowering time by modulating the day-length response, By using near-isogenic lines with functional or deficient alleles of several rice flowering-time genes, we observed significant digenetic interactions between Hd16 and four other flowering-time genes (Ghd7, Hd1, DTH8 and Hd2)
  • CKI~EL1~Hd16, Ghd7, Hd16, a gene for casein kinase I, is involved in the control of rice flowering time by modulating the day-length response, By using near-isogenic lines with functional or deficient alleles of several rice flowering-time genes, we observed significant digenetic interactions between Hd16 and four other flowering-time genes (Ghd7, Hd1, DTH8 and Hd2)
  • CKI~EL1~Hd16, Ghd7, Hd16, a gene for casein kinase I, is involved in the control of rice flowering time by modulating the day-length response, Biochemical characterization indicated that the functional Hd16 recombinant protein specifically phosphorylated Ghd7
  • CKI~EL1~Hd16, Ghd7, Hd16, a gene for casein kinase I, is involved in the control of rice flowering time by modulating the day-length response, These results demonstrate that Hd16 acts as an inhibitor in the rice flowering pathway by enhancing the photoperiod response as a result of the phosphorylation of Ghd7
  • Ghd7, Hd1, Hd16, a gene for casein kinase I, is involved in the control of rice flowering time by modulating the day-length response, By using near-isogenic lines with functional or deficient alleles of several rice flowering-time genes, we observed significant digenetic interactions between Hd16 and four other flowering-time genes (Ghd7, Hd1, DTH8 and Hd2)
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, Days to heading 7, a major quantitative locus determining photoperiod sensitivity and regional adaptation in rice., Further, we find that haplotype combinations of DTH7 with Grain number, plant height, and heading date 7 (Ghd7) and DTH8 correlate well with the heading date and grain yield of rice under different photoperiod conditions
  • CKI~EL1~Hd16, Ghd7, Casein Kinases I and 2伪 Phosphorylate Oryza Sativa Pseudo-Response Regulator 37 OsPRR37 in Photoperiodic Flowering in Rice, In floral induction, Hd16 acts upstream of Ghd7 and CKI interacts with and phosphorylates Ghd7
  • FKF1~OsFKF1, Ghd7, Rice FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 OsFKF1 promotes flowering independent of photoperiod., Moreover, OsFKF1 can upregulate Ehd1 expression under blue light treatment, without affecting the expression of Ehd2 and Ghd7
  • FKF1~OsFKF1, Ghd7, Rice FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 OsFKF1 promotes flowering independent of photoperiod., In contrast to the LD-specific floral activator Arabidopsis FKF1, OsFKF1 likely acts as an autonomous floral activator because it promotes flowering independent of photoperiod, probably via its distinct roles in controlling expression of rice-specific genes including Ehd2, Ghd7, and Ehd1
  • Ghd7, Hd1, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice.
  • Ghd7, Hd1, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Map-based cloning demonstrated that the gene largely affecting the interaction between Ghd7 and Ghd8 was Hd1
  • Ghd7, Hd1, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Natural variation analysis showed that a combination of loss-of-function alleles of Ghd7, Ghd8 and Hd1 contributes to the expansion of rice cultivars to higher latitudes; by contrast, a combination of pre-existing strong alleles of Ghd7, Ghd8 and functional Hd1 (referred as SSF) is exclusively found where ancestral Asian cultivars originated
  • Ghd7, Hd1, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Our results indicate that the combinations of Ghd7, Ghd8 and Hd1 largely define the ecogeographical adaptation and yield potential in rice cultivars
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice.
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., We employed a map-based cloning approach to isolate a heading date gene, which coordinated the interaction between Ghd7 and Ghd8 to greatly delay rice heading
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Map-based cloning demonstrated that the gene largely affecting the interaction between Ghd7 and Ghd8 was Hd1
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Natural variation analysis showed that a combination of loss-of-function alleles of Ghd7, Ghd8 and Hd1 contributes to the expansion of rice cultivars to higher latitudes; by contrast, a combination of pre-existing strong alleles of Ghd7, Ghd8 and functional Hd1 (referred as SSF) is exclusively found where ancestral Asian cultivars originated
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Combinations of the Ghd7, Ghd8 and Hd1 genes largely define the ecogeographical adaptation and yield potential of cultivated rice., Our results indicate that the combinations of Ghd7, Ghd8 and Hd1 largely define the ecogeographical adaptation and yield potential in rice cultivars
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, OsPRR37 and Ghd7 are the major genes for general combining ability of DTH, PH and SPP in rice., OsPRR37 and Ghd7 are the major genes for general combining ability of DTH, PH and SPP in rice.
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, OsPRR37 and Ghd7 are the major genes for general combining ability of DTH, PH and SPP in rice., Both GCA1 and GCA2 were loss-of-function gene in low-GCA parent and gain-of-function gene in high-GCA parent, encoding the putative Pseudo-Response Regulators, OsPRR37 and Ghd7, respectively
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, OsPRR37 and Ghd7 are the major genes for general combining ability of DTH, PH and SPP in rice., Our results demonstrate that two GCA loci associate with OsPRR37 and Ghd7 and reveal that the genes responsible for important agronomic traits could simultaneously account for GCA effects
  • Ghd7, OsCOL10, OsCOL10, a CONSTANS-like gene, functions as a flowering-time repressor downstream of Ghd7 in rice., OsCOL10, a CONSTANS-like gene, functions as a flowering-time repressor downstream of Ghd7 in rice.
  • Ghd7, OsCOL10, OsCOL10, a CONSTANS-like gene, functions as a flowering-time repressor downstream of Ghd7 in rice., Transcripts of OsCOL10 are more abundant in the plants carrying a functional Ghd7 allele or over-expressing Ghd7 than in the Ghd7-deficient ones, thus placing OsCOL10 downstream of Ghd7
  • Ghd7, OsCOL10, OsCOL10, a CONSTANS-like gene, functions as a flowering-time repressor downstream of Ghd7 in rice., Together, we conclude that OsCOL10 functions as a flowering-time repressor that links between Ghd7 and Ehd1 in rice
  • Ehd1, Ghd7, Hd1,a CONSTANS Orthlog in Rice, Functions as an Ehd1 Repressor Through Interaction with Monocot-Specific CCT-Domain Protein Ghd7., Hd1,a CONSTANS Orthlog in Rice, Functions as an Ehd1 Repressor Through Interaction with Monocot-Specific CCT-Domain Protein Ghd7.
  • Ehd1, Ghd7, Hd1,a CONSTANS Orthlog in Rice, Functions as an Ehd1 Repressor Through Interaction with Monocot-Specific CCT-Domain Protein Ghd7., Here, we report biological interactions between Ghd7 and Hd1, which together repress Early heading date 1 (Ehd1), a key floral inducer under non-inductive long-day (LD) conditions
  • Ghd7, Hd1, Hd1,a CONSTANS Orthlog in Rice, Functions as an Ehd1 Repressor Through Interaction with Monocot-Specific CCT-Domain Protein Ghd7., Here, we report biological interactions between Ghd7 and Hd1, which together repress Early heading date 1 (Ehd1), a key floral inducer under non-inductive long-day (LD) conditions
  • Ghd7, Hd1, Hd1,a CONSTANS Orthlog in Rice, Functions as an Ehd1 Repressor Through Interaction with Monocot-Specific CCT-Domain Protein Ghd7., These findings imply that Hd1, an evolutionally conserved transcriptional activator, can function as a strong transcriptional repressor within a monocot-specific flowering-time pathway through with Ghd7
  • Ghd7, PHYA~OsPhyA, OsPhyA modulates rice flowering time mainly through OsGI under short days and Ghd7 under long days in the absence of phytochrome B., OsPhyA modulates rice flowering time mainly through OsGI under short days and Ghd7 under long days in the absence of phytochrome B.
  • Ghd7, PHYA~OsPhyA, OsPhyA modulates rice flowering time mainly through OsGI under short days and Ghd7 under long days in the absence of phytochrome B., These results indicated that OsPhyA influences flowering time mainly by affecting the expression of OsGI under SD and Ghd7 under LD when phytochrome B is absent
  • Ghd7, Se14, Se14, encoding a JmjC domain-containing protein, plays key roles in long-day suppression of rice flowering through the demethylation of H3K4me3 of RFT1., We found that Se14 is independent of the known photoperiod-sensitive genes, such as Hd1 and Ghd7, and is identical to Os03g0151300, which encodes a Jumonji C (JmjC) domain-containing protein
  • Ghd7, ROC4, GL2-type homeobox gene Roc4 in rice promotes flowering time preferentially under long days by repressing Ghd7, GL2-type homeobox gene Roc4 in rice promotes flowering time preferentially under long days by repressing Ghd7
  • Ghd7, ROC4, GL2-type homeobox gene Roc4 in rice promotes flowering time preferentially under long days by repressing Ghd7, Whereas constitutive overexpression of Roc4 in Dongjin japonica rice, which carries active Ghd7, also caused LD-preferential early flowering, its overexpression in Longjing27 rice, which is defective in functional Ghd7, did not produce the same result
  • Ghd7, ROC4, GL2-type homeobox gene Roc4 in rice promotes flowering time preferentially under long days by repressing Ghd7, This confirmed that Roc4 regulates flowering time mainly through Ghd7
  • Ghd7, ROC4, GL2-type homeobox gene Roc4 in rice promotes flowering time preferentially under long days by repressing Ghd7, All of these findings are evidence that Roc4 is an LD-preferential flowering enhancer that functions downstream of phytochromes and OsGI, but upstream of Ghd7
  • Ghd2~OsK, Ghd7, Ghd2, a CONSTANS-like gene, confers drought sensitivity through regulation of senescence in rice., Here, we found that a CO-like gene, Ghd2 (Grain number, plant height, and heading date2), which can increase the yield potential under normal growth condition just like its homologue Ghd7, is involved in the regulation of leaf senescence and drought resistance
  • Ghd7, OsCOL10, Flowering time regulation by the CONSTANS-Like gene OsCOL10., Moreover, we also showed that OsCOL10 acts downstream of Ghd7, a key LD-specific flowering repressor by reducing expression of Ehd1
  • Ghd7, OsCOL10, Flowering time regulation by the CONSTANS-Like gene OsCOL10., Collectively, our finding identifies OsCOL10 functioning as a flowering-time repressor that links between Ghd7 and Ehd1 in rice
  • Ghd7, OsCOL16, OsCOL16, encoding a CONSTANS-like protein, represses flowering by up-regulating Ghd7 expression in rice., OsCOL16, encoding a CONSTANS-like protein, represses flowering by up-regulating Ghd7 expression in rice.
  • Ghd7, OsCOL16, OsCOL16, encoding a CONSTANS-like protein, represses flowering by up-regulating Ghd7 expression in rice., We determined that OsCOL16 up-regulates the expression of the floral repressor Ghd7, leading to down-regulation of the expression of Ehd1, Hd3a, and RFT1
  • Ehd1, Ghd7, Alternative functions of Hd1 in repressing or promoting heading are determined by Ghd7 status under long-day conditions., The interaction between proteins Ghd7 and Hd1 occurred through binding of the CCT domain of Ghd7 to the transcription-activating domain of Hd1, resulting in suppression of Ehd1 and florigen gene expression
  • Ghd7, Hd1, Alternative functions of Hd1 in repressing or promoting heading are determined by Ghd7 status under long-day conditions., Alternative functions of Hd1 in repressing or promoting heading are determined by Ghd7 status under long-day conditions.
  • Ghd7, Hd1, Alternative functions of Hd1 in repressing or promoting heading are determined by Ghd7 status under long-day conditions., Comparative analysis of two sets of near isogenic lines of Hd1 in MH63 and ZS97 backgrounds indicated that the alternative functions of Hd1 in promoting or suppressing heading under LD are dependent on the previously cloned flowering repressor gene Ghd7
  • Ghd7, Hd1, Alternative functions of Hd1 in repressing or promoting heading are determined by Ghd7 status under long-day conditions., The interaction between proteins Ghd7 and Hd1 occurred through binding of the CCT domain of Ghd7 to the transcription-activating domain of Hd1, resulting in suppression of Ehd1 and florigen gene expression
  • Ghd7, Hd1, Alternative functions of Hd1 in repressing or promoting heading are determined by Ghd7 status under long-day conditions., These findings suggest that Hd1 alone essentially acts as a promoter of heading date, and the protein interaction between Ghd7 and Hd1 determines photoperiod sensitivity and integrated Hd1-mediated and Ehd1-mediated flowering pathways in rice
  • Ghd7, OsCOL15, The rice CONSTANS-like protein OsCOL15 suppresses flowering by promoting Ghd7 and repressing RID1., The rice CONSTANS-like protein OsCOL15 suppresses flowering by promoting Ghd7 and repressing RID1.
  • Ghd7, OsCOL15, The rice CONSTANS-like protein OsCOL15 suppresses flowering by promoting Ghd7 and repressing RID1., Real-time quantitative RT-PCR analysis of flowering regulator gene expression suggested that OsCOL15 suppresses flowering by up-regulating the flowering repressor Grain number, plant height and heading date 7 (Ghd7) and down-regulating the flowering activator Rice Indeterminate 1 (RID1), thus leading to the down-regulation of the flowering activators Early heading date 1, Heading date 3a, and RICE FLOWERING LOCUS T1
  • Ghd7, OsCOL15, The rice CONSTANS-like protein OsCOL15 suppresses flowering by promoting Ghd7 and repressing RID1., These results demonstrate that OsCOL15 is an important floral regulator acting upstream of Ghd7 and RID1 in the rice photoperiodic flowering-time regulatory network
  • Ghd7, Hd1, Genetic interaction involving photoperiod-responsive Hd1 promotes early flowering under long-day conditions in rice., Based on the phenotypic and genotypic data of the NILs, and NIL mapping population and the transcript abundance of key flowering pathway genes, we conclude that Hd1 and its interaction with a novel gene other than Ghd7 play an important role in controlling flowering under LD conditions
  • Ghd7, OsMFT1, OsMFT1 increases spikelets per panicle and delays heading date in rice by suppressing Ehd1, FZP and SEPALLATA-like genes., Overexpression of OsMFT1 significantly suppressed Ehd1 expression, and Ghd7 up-regulated OsMFT1 expression
  • Ghd7, OsMFT1, OsMFT1 increases spikelets per panicle and delays heading date in rice by suppressing Ehd1, FZP and SEPALLATA-like genes., Double mutants showed that OsMFT1 acted downstream of Ghd7
  • Ghd7, OsMFT1, OsMFT1 increases spikelets per panicle and delays heading date in rice by suppressing Ehd1, FZP and SEPALLATA-like genes., Therefore, OsMFT1 is a suppressor of flowering acting downstream of Ghd7 and upstream of Ehd1, and a positive regulator of panicle architecture
  • Ghd7, Hd17~Ef7~OsELF3-1~OsELF3.1~OsELF3, Genetic relationship between phytochromes and OsELF3-1 reveals the mode of regulation for the suppression of phytochrome signaling in rice., Although the oself3-1 mutation recovered Ghd7 expression in the se5 background, there was a lack of Ghd7 expression in the phyAphyBphyC triple mutant background
  • Ghd7, Hd17~Ef7~OsELF3-1~OsELF3.1~OsELF3, Genetic relationship between phytochromes and OsELF3-1 reveals the mode of regulation for the suppression of phytochrome signaling in rice., These observations suggest OsELF3-1 represses Ghd7 expression by inhibiting the phytochrome signaling pathway
  • Ghd7, Hd1, Loss-of-Function Alleles of Heading date 1 Hd1 Are Associated With Adaptation of Temperate Japonica Rice Plants to the Tropical Region., We analyzed the 45 diverse rice accessions and 12 tropical-adapted temperate japonica lines for the allele types of seven major flowering genes Hd1, OsPPR37, DTH8, Ghd7, Ehd1, RFT1, and Hd3a and flowering time under three different field conditions in temperate and tropical locations
  • Ghd7, Hd1, Importance of the Interaction between Heading Date Genes Hd1 and Ghd7 for Controlling Yield Traits in Rice., Importance of the Interaction between Heading Date Genes Hd1 and Ghd7 for Controlling Yield Traits in Rice.
  • Ghd7, Hd1, Importance of the Interaction between Heading Date Genes Hd1 and Ghd7 for Controlling Yield Traits in Rice., In this study, influences of interaction between Hd1 and Ghd7 on flowering time and yield traits were analyzed using near isogenic lines derived from a cross between indica rice cultivars ZS97 and MY46
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, Switching genetic effects of the flowering time gene Hd1 in LD conditions by Ghd7 and OsPRR37 in rice., Switching genetic effects of the flowering time gene Hd1 in LD conditions by Ghd7 and OsPRR37 in rice.
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, Switching genetic effects of the flowering time gene Hd1 in LD conditions by Ghd7 and OsPRR37 in rice., We herein show genetic interactions among three LD repressor genes: Hd1, Grain number, plant height and heading date 7 (Ghd7), and Oryza sativa Pseudo-Response Regulator37 (OsPRR37)
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, Switching genetic effects of the flowering time gene Hd1 in LD conditions by Ghd7 and OsPRR37 in rice., Genetic analyses, including segregation analyses, evaluations of near isogenic lines, and transformation for flowering time demonstrated that Hd1 promoted flowering time in inductive SD and non-inductive LD conditions in genetic condition of loss-of-function Ghd7 and OsPRR37 (ghd7osprr37) in rice
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, Switching genetic effects of the flowering time gene Hd1 in LD conditions by Ghd7 and OsPRR37 in rice., Functional Ghd7 or OsPRR37 may switch the genetic effects of Hd1 from the promotion to the delay of flowering times in LD conditions
  • Ghd7, OsGI, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice.
  • Ghd7, OsGI, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., We also found that co-expressing OsGI with Ghd7 causes reduced accumulation of Ghd7 protein and partially suppresses the delayed flowering phenotype in the wild type background, suggesting that phytochromes and OsGI play antagonist roles in regulating Ghd7 protein stability and flowering time
  • Ghd7, OsGI, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., We show that OsPHYA, OsPHYB and OsGI could directly interact with Ghd7
  • Ghd7, OsGI, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., Interestingly, OsPHYA and OsPHYB could inhibit the interaction between OsGI and Ghd7, and thus helping to stabilize Ghd7 protein
  • Ghd7, OsGI, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., Our results revealed a new level of Ghd7 regulation by phytochromes and OsGI in photoperiodic control of flowering in rice
  • Ghd7, PHYA~OsPhyA, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., We show that OsPHYA, OsPHYB and OsGI could directly interact with Ghd7
  • Ghd7, PHYA~OsPhyA, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., Interestingly, OsPHYA and OsPHYB could inhibit the interaction between OsGI and Ghd7, and thus helping to stabilize Ghd7 protein
  • Ghd7, PHYB~OsphyB, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., We show that OsPHYA, OsPHYB and OsGI could directly interact with Ghd7
  • Ghd7, PHYB~OsphyB, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., Interestingly, OsPHYA and OsPHYB could inhibit the interaction between OsGI and Ghd7, and thus helping to stabilize Ghd7 protein
  • Ghd7, Se5~OsHY1~OsHO1~YGL2~YE1~PE-1, Posttranscriptional regulation of Ghd7 protein stability by phytochrome and OsGI in photoperiodic control of flowering in rice., We found that constitutive expression of Ghd7 delays flowering in the wild type background, but not in the se5 mutant background (deficient in functional phytochromes) under LD and that Ghd7 protein fails to accumulate in the se5 mutant
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, Genetic Interactions Among Ghd7, Ghd8, OsPRR37 and Hd1 Contribute to Large Variation in Heading Date in Rice., Genetic Interactions Among Ghd7, Ghd8, OsPRR37 and Hd1 Contribute to Large Variation in Heading Date in Rice.
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7., Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7.
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7., Ghd8 and Ghd7, two major flowering genes, have similar functions and large pleiotropic effects in controlling the heading date, plant height and grain yield of rice
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7., In this study, we investigated the genetic interaction between Ghd8 and Ghd7 by using a set of near-isogenic lines and a panel of natural germplasm accessions in rice
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7., Both functional Ghd8 and Ghd7 are pivotal for rice photoperiod sensitivity controlled by Hd1 and Hd3a
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7., GHD8 could form a heterotrimeric complex with HD1 and OsHAP5b to activate the transcription of Ghd7 by binding directly to the promoter region of Ghd7, which contains the CCAAT-box motif
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Ghd8 controls rice photoperiod sensitivity by forming a complex that interacts with Ghd7., The results of this study help to elucidate the genetic and molecular bases of Ghd8 and Ghd7 interactions, indicating that Ghd8 acts upstream of Ghd7 to activate its transcription, which inhibits Hd3a expression and thus affects flowering time and rice adaptation
  • Ghd7, OsCOL4, A Combination of Long-Day Suppressor Genes Contributes to the Northward Expansion of Rice , Here, we report the analysis of genetic variation in eight long-day flowering suppressor genes (Hd1, DTH8, Ghd7, OsCOL4, DTH7, Hd6, Se5, and PhyB) and the phylogenetic relationship of eight genes
  • Ghd7, OsCOL4, A Combination of Long-Day Suppressor Genes Contributes to the Northward Expansion of Rice , Genetic variations in DTH8, Ghd7, Hd1, DTH7, PhyB, and OsCOL4 are correlated with differences in heading date and the correlation between the genetic diversity of Hd6 and Se5 and rice heading data are weak
  • Ghd7, OsCOL4, A Combination of Long-Day Suppressor Genes Contributes to the Northward Expansion of Rice , One group of haplotypes of DTH8, Ghd7, Hd1, DTH7, PhyB, and OsCOL4 are associated with earlier heading dates and appear to have accumulated during the northward expansion of rice cultivation
  • Ghd7, OsCOL4, A Combination of Long-Day Suppressor Genes Contributes to the Northward Expansion of Rice , A minimum of four group A alleles of DTH8, Ghd7, Hd1, DTH7, PhyB, and OsCOL4 are required for the growth of cultivated rice at latitudes above 30°N
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Strong photoperiod sensitivity is controlled by cooperation and competition among Hd1, Ghd7 and DTH8 in rice heading, Strong photoperiod sensitivity is controlled by cooperation and competition among Hd1, Ghd7 and DTH8 in rice heading
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Strong photoperiod sensitivity is controlled by cooperation and competition among Hd1, Ghd7 and DTH8 in rice heading, We created a set of isogenic lines among the core PS-flowering genes Hd1, Ghd7 and DTH8 using CRISPR mutagenesis, to systematically dissect their genetic relationships under different day-lengths
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Strong photoperiod sensitivity is controlled by cooperation and competition among Hd1, Ghd7 and DTH8 in rice heading, However, under LD conditions, Hd1 promotes Ghd7 expression and is recruited by Ghd7 and/or DTH8 to form repressive complexes that collaboratively suppress the Ehd1-Hd3a/RFT1 pathway to block heading, but under SD conditions Hd1 competes with the complexes to promote Hd3a/RFT1 expression, playing a tradeoff relationship with PS flowering
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Strong photoperiod sensitivity is controlled by cooperation and competition among Hd1, Ghd7 and DTH8 in rice heading, Natural allelic variations of Hd1, Ghd7 and DTH8 in rice populations have resulted in various PS performances
  • Ehd1, Ghd7, Transcriptional and post-transcriptional regulation of heading date in rice, In this review, we summarize current progress on transcriptional and post-transcriptional regulation of heading date in rice with emphasis on post-translational modifications of key regulators, including Heading Date 1 (Hd1), Early Heading Date 1 (Ehd1), Grain Number, Plant Height, and Heading Date7 (Ghd7)
  • Ghd7, Hd1, Transcriptional and post-transcriptional regulation of heading date in rice, In this review, we summarize current progress on transcriptional and post-transcriptional regulation of heading date in rice with emphasis on post-translational modifications of key regulators, including Heading Date 1 (Hd1), Early Heading Date 1 (Ehd1), Grain Number, Plant Height, and Heading Date7 (Ghd7)
  • Ghd7, OsBZR1~BZR1, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression
  • Ghd7, OsBZR1~BZR1, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression, We further show that GRAIN NUMBER, PLANT HEIGHT, and HEADING DATE 7 (Ghd7), a central regulator of growth, development, and the stress response, is a direct target of OsBZR1
  • Ghd7, OsBZR1~BZR1, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression, Together, our study suggests that HDA703, a histone H4 deacetylase, interacts with OsBZR1 to regulate rice BR signaling, growth, and heading date through epigenetic regulation of Ghd7
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, OsPRR37 Alternatively Promotes Heading Date Through Suppressing the Expression of Ghd7 in the Japonica Variety Zhonghua 11 under Natural Long-Day Conditions, OsPRR37 Alternatively Promotes Heading Date Through Suppressing the Expression of Ghd7 in the Japonica Variety Zhonghua 11 under Natural Long-Day Conditions
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, OsPRR37 Alternatively Promotes Heading Date Through Suppressing the Expression of Ghd7 in the Japonica Variety Zhonghua 11 under Natural Long-Day Conditions, Transcriptional analysis revealed that OsPRR37 suppressed Ghd7 expression in both ZH11 background under NLD conditions and the Zhenshan 97 background under natural short-day conditions
  • Ghd7, Ghd7.1~Hd2~OsPRR37~DTH7, OsPRR37 Alternatively Promotes Heading Date Through Suppressing the Expression of Ghd7 in the Japonica Variety Zhonghua 11 under Natural Long-Day Conditions, Genetic analysis indicated that the promotion of heading date and reduction in grain yield by OsPRR37 were partially dependent on Ghd7
  • Ehd1, Ghd7, High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice, We also revealed that PhyB can control Ghd7 repressor activity as a temperature sensor to inhibit Ehd1, Hd3a, and RFT1 at lower temperatures, likely through a post-transcriptional regulation, despite inductive photoperiod conditions
  • Ghd7, Hd1, High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice, In addition to delayed flowering because of low growth rates, we found that photoperiodic flowering is clearly enhanced by both Hd1 and Ghd7 genes under low-temperature conditions in rice
  • Ghd7, Hd3a, High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice, We also revealed that PhyB can control Ghd7 repressor activity as a temperature sensor to inhibit Ehd1, Hd3a, and RFT1 at lower temperatures, likely through a post-transcriptional regulation, despite inductive photoperiod conditions
  • Ghd7, OsGI-Hd1-Hd3a~RFT1, High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice, We also revealed that PhyB can control Ghd7 repressor activity as a temperature sensor to inhibit Ehd1, Hd3a, and RFT1 at lower temperatures, likely through a post-transcriptional regulation, despite inductive photoperiod conditions
  • Ghd7, OsGI-Hd1-Hd3a~RFT1, High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice, Furthermore, we found that rapid reduction of Ghd7 mRNA under high-temperature conditions can lead to mRNA increase in a rice florigen gene, RFT1
  • Ghd7, PHYB~OsphyB, High Ambient Temperatures Inhibit Ghd7-mediated Flowering Repression in Rice, We also revealed that PhyB can control Ghd7 repressor activity as a temperature sensor to inhibit Ehd1, Hd3a, and RFT1 at lower temperatures, likely through a post-transcriptional regulation, despite inductive photoperiod conditions
  • Ghd7, OsLHY, mediated pathways in rice Oryza sativa L.., Furthermore, the expression of the flowering activators Ehd1, Hd3a and RFT1 was down-regulated and flowering repressors Hd1 and Ghd7 was up-regulated in the oslhy mutant under LD conditions
  • Ghd7, OsLHY, mediated pathways in rice Oryza sativa L.., Dual-luciferase assays showed that OsLHY repressed the transcription of OsGI, Hd1, Ghd7, Hd3a, RFT1 and OsELF3, and activated the transcription of Ehd1
  • Ghd7, Hd17~Ef7~OsELF3-1~OsELF3.1~OsELF3, mediated pathways in rice Oryza sativa L.., Dual-luciferase assays showed that OsLHY repressed the transcription of OsGI, Hd1, Ghd7, Hd3a, RFT1 and OsELF3, and activated the transcription of Ehd1
  • Ghd7, OsHUB2~FRRP1, OsHUB2 inhibits function of OsTrx1 in heading date in rice., The expression of Hd3a, RFT1, and Ehd1 was induced and the transcript levels of Hd1, Ghd7, OsCCA1, OsGI, OsFKF1, and OsTOC1 were reduced under long-day conditions, whereas RFT1 and Ehd1 expression was induced in oshub2 mutants under short-day conditions
  • Ghd7, Hd1, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits.
  • Ghd7, Hd1, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., The core heading date genes Hd1, Ghd7, DTH8, and PRR37 act synergistically in regulating the PS
  • Ghd7, Hd1, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., In this study, we systematically analyze the heading date, PS, and agronomic traits of eight homozygous lines with various combinations of Hd1, Ghd7, and DTH8 alleles in the prr37 background under long-day (LD) and short-day (SD) conditions, respectively
  • Ghd7, Hd1, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., However, under LDs, Hd1 suppresses flowering, in coordination with functional Ghd7 or with Ghd7 and DTH8
  • Ghd7, Hd1, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., Lines carrying Ghd7 and DTH8 (with hd1) show delayed heading and improve agronomic traits
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits.
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., The core heading date genes Hd1, Ghd7, DTH8, and PRR37 act synergistically in regulating the PS
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., In this study, we systematically analyze the heading date, PS, and agronomic traits of eight homozygous lines with various combinations of Hd1, Ghd7, and DTH8 alleles in the prr37 background under long-day (LD) and short-day (SD) conditions, respectively
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., However, under LDs, Hd1 suppresses flowering, in coordination with functional Ghd7 or with Ghd7 and DTH8
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, Hd1, Ghd7, and DTH8 synergistically determine the rice heading date and yield-related agronomic traits., Lines carrying Ghd7 and DTH8 (with hd1) show delayed heading and improve agronomic traits
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, DTH8 overexpression induces early flowering, boosts yield, and improves stress recovery in rice cv IR64., DTH8 up-regulates the transcription of RFT1, Hd3a, GHD7, MOC1, and RCN1 in IR64 at the pre-flowering stage and plays a role in early flowering, increased number of tillers, enhanced panicle branching, and improved tolerance towards drought and salinity stress at the reproductive stage
  • Ghd7, OsLUX~OsPCL1, The clock component OsLUX regulates rice heading through recruiting OsELF3-1 and OsELF4s to repress Hd1 and Ghd7., The clock component OsLUX regulates rice heading through recruiting OsELF3-1 and OsELF4s to repress Hd1 and Ghd7.
  • Ghd7, Hd17~Ef7~OsELF3-1~OsELF3.1~OsELF3, The clock component OsLUX regulates rice heading through recruiting OsELF3-1 and OsELF4s to repress Hd1 and Ghd7., The clock component OsLUX regulates rice heading through recruiting OsELF3-1 and OsELF4s to repress Hd1 and Ghd7.
  • Ghd7, HDA703, Ammonium protects rice against rice stripe virus by activating HDA703/OsBZR1-mediated BR signaling., Consistently, increase of the expression of HDA703 or decrease of the expression of Ghd7 enhances rice resistance to RSV
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, The amino acid residue E96 orf Ghd8 is crucial for the formation of the flowering repression complex Ghd7-Ghd8-OsHAP5C in rice., Biochemical assays showed that Ghd8 interacts with OsHAP5C and Ghd7 both in vivo and in vitro
  • Ghd7, Hd5~DTH8~Ghd8~OsHAP3H~LHD1~EF8~CAR8~OsNF-YB11, The amino acid residue E96 orf Ghd8 is crucial for the formation of the flowering repression complex Ghd7-Ghd8-OsHAP5C in rice., Surprisingly, a point mutation E96K in 伪2 helix of Ghd8 HFD domain destroyed its ability interacting with Ghd7
  • Ghd7, OsHAP5C, The amino acid residue E96 orf Ghd8 is crucial for the formation of the flowering repression complex Ghd7-Ghd8-OsHAP5C in rice., Biochemical assays showed that Ghd8 interacts with OsHAP5C and Ghd7 both in vivo and in vitro
  • Ghd7, OsLHY, Bifunctional regulators of photoperiodic flowering in short day plant rice., Subsequently, numerous dual function regulators, such as phytochromes, Ghd7, DHT8, OsPRR37, OsGI, OsLHY, and OsELF3, were gradually identified

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