PRP5,OsRH42

• Symbol: PRP5,OsRH42
• MSU: LOC_Os08g06344
• RAPdb: Os08g0159900

• microRNAs targeting DEAD-box helicases are involved in salinity stress response in rice Oryza sativa L., 2012, BMC Plant Biol.
• DEAD-box RNA helicase 42 plays a critical role in pre-mRNA splicing under cold stress., 2019, Plant Physiol.

Genbank accession number

• OsRH42 expression is tightly coupled to temperature fluctuation, and OsRH42 is localized in the splicing speckles and interacts directly with U2 snRNA
• Retarded pre-mRNA splicing and plant growth defects were exhibited by OsRH42-knockdown transgenic lines at low temperatures, thus indicating that OsRH42 performs an essential role in ensuring accurate pre-mRNA splicing and normal plant growth under low ambient temperature
• Combined, these results indicate that accurate control of OsRH42 homeostasis is essential for rice plants to respond to changes in ambient temperature
• Unexpectedly, our results show that OsRH42 overexpression significantly disrupts the pre-mRNA splicing pathway, causing retarded plant growth and reducing plant cold tolerance