- Information
- Symbol: BSR1
- MSU: LOC_Os09g36320
- RAPdb: Os09g0533600
- Publication
- Screening for resistance against Pseudomonas syringae in rice-FOX Arabidopsis lines identified a putative receptor-like cytoplasmic kinase gene that confers resistance to major bacterial and fungal pathogens in Arabidopsis and rice, 2011, Plant Biotechnol J.
- Tyrosine phosphorylation of a receptor-like cytoplasmic kinase, BSR1, plays a crucial role in resistance to multiple pathogens in rice., 2018, Plant J.
- Broad-Spectrum Disease Resistance Conferred by the Overexpression of Rice RLCK BSR1 Results from an Enhanced Immune Response to Multiple MAMPs., 2019, Int J Mol Sci.
- Overexpressed BSR1-Mediated Enhancement of Disease Resistance Depends on the MAMP-Recognition System, 2020, Int J Mol Sci.
- Genbank accession number
- Key message
- Importantly, tyrosine phosphorylation of BSR1 was critical for proper localization of BSR1 in rice cells and played a crucial role in BSR1-mediated resistance to multiple diseases, as evidenced by compromised disease resistance in transgenic plants overexpressing a mutant BSR1 in which Tyr-63 was substituted with Ala
- Overall, our data indicate that BSR1 is a nonreceptor dual-specificity kinase and that both tyrosine and serine/threonine kinase activities are critical for the normal functioning of BSR1 in the resistance to multiple pathogens
- In the present study, we report that BSR1 is a functional protein kinase that autophosphorylates and transphosphorylates an artificial substrate, in vitro
- Although BSR1 is classified as a serine/threonine kinase, it was shown to autophosphorylate on tyrosine as well as on serine/threonine residues when expressed in bacteria, demonstrating that it is a dual-specificity kinase
- Here we analyzed immune responses using rice suspension-cultured cells and sliced leaf blades overexpressing BSR1
- BSR1 overexpression enhances MAMP-triggered production of hydrogen peroxide (H2O2) and transcriptional activation of the defense-related gene in cultured cells and leaf strips
- Broad-Spectrum Disease Resistance Conferred by the Overexpression of Rice RLCK BSR1 Results from an Enhanced Immune Response to Multiple MAMPs.
- Furthermore, the co-cultivation of leaves with conidia of the blast fungus revealed that BSR1 overexpression allowed host plants to produce detectable oxidative bursts against compatible pathogens
- However, it remains unclear how overexpressed BSR1 reinforces plant immunity
- BSR1 was also involved in the immune responses triggered by peptidoglycan and lipopolysaccharide
- Overexpression of BSR1 confers strong resistance against fungal and bacterial pathogens
- In the background of BSR1 overaccumulation, the knockout of OsCERK1 nearly abolished the enhancement of blast resistance
- Our recent study revealed that MAMP-triggered immune responses are mediated by BSR1 in wild-type rice and are hyperactivated in BSR1-overexpressing rice
- Connection
- BSR1, OsCERK1, Overexpressed BSR1-Mediated Enhancement of Disease Resistance Depends on the MAMP-Recognition System, In the background of BSR1 overaccumulation, the knockout of OsCERK1 nearly abolished the enhancement of blast resistance
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