NF-YC12,OsNF-YC12

• Symbol: NF-YC12,OsNF-YC12
• MSU: LOC_Os10g11580
• RAPdb: Os10g0191900

• NF-YB1-YC12-bHLH144 complex directly activates Wx to regulate grain quality in rice Oryza sativa L.., 2018, Plant Biotechnol J.
• NF-YC12 is a key multi-functional regulator of accumulation of seed storage substances in rice., 2019, J Exp Bot.
• Transcription factor OsNF-YB9 regulates reproductive growth and development in rice., 2019, Planta.

Genbank accession number

• NF-YB1-YC12-bHLH144 complex directly activates Wx to regulate grain quality in rice (Oryza sativa L.).
• NF-YC12 and bHLH144 maintain NF-YB1 stability from the degradation mediated by ubiquitin/26S proteasome, while NF-YB1 directly binds to the ‘G-box’ domain of Wx promoter and activates Wx transcription, hence to regulate rice grain quality.
• Knockout of NF-YC12 significantly decreased grain weight as well as altering starch and protein accumulation and starch granule formation.
• This study demonstrates a transcriptional regulatory network involving NF-YC12, which coordinates multiple pathways to regulate endosperm development and the accumulation of storage substances in rice seeds.