PAIR3

2015-01-20 | Categories genes  | Tags meiotic  meiosis  sterility  pollen  reproductive 

• Information
  • Symbol: PAIR3
  • MSU: LOC_Os10g26560
  • RAPdb: Os10g0405500
• Publication
  • Mutation of the rice gene PAIR3 results in lack of bivalent formation in meiosis, 2009, Plant J.
  • The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis, 2012, Plant J.
  • Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells, 2020, Front Plant Sci.
• Genbank accession number
  • FJ449712
• Key message
  • Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal
  • In this study, we identified a novel gene, PAIR3 (HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS 3), required for homologous chromosome pairing and synapsis in rice
  • PAIR3 is preferentially expressed in reproductive organs, especially in pollen mother cells and the ovule tissues during meiosis
  • Our results suggest that PAIR3 plays a crucial role in homologous chromosome pairing and synapsis in meiosis
  • Mutation of the rice gene PAIR3 results in lack of bivalent formation in meiosis
  • Two independent alleles, designated pair3-1 and pair3-2, were identified in our T-DNA insertional mutant library which could not form bivalents due to failure of homologous chromosome pairing and synapsis at diakinesis, resulting in sterility in both male and female gametes
• Connection
  • OsCOM1, PAIR3, The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis, Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal
  • OsRad21-4~OsREC8, PAIR3, The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis, Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal
  • PAIR2, PAIR3, The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis, Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal
  • MER3~RCK, PAIR3, The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis, Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal
  • PAIR3, ZEP1~OsZEP, The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis, Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal
  • OsDMC1~DMC1B~OsDMC1B, PAIR3, OsDMC1 is not required for homologous pairing in rice meiosis., In the absence of OsDMC1, early recombination events probably occur normally, leading to normal localization of γH2AX, PAIR3, OsMRE11, OsCOM1 and OsRAD51C
  • OsDMC1~DMC1B~OsDMC1B, PAIR3, OsDMC1 is not required for homologous pairing in rice meiosis., Moreover, OsDMC1 was not detected in pairing-defective mutants, such as pair2, pair3, Oscom1 and Osrad51c, while it was loaded onto meiotic chromosomes in zep1, Osmer3, Oszip4 and Oshei10

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