OsHLP1

2015-01-20 | Categories genes | Tags transcription factor resistance disease disease resistance blast stress magnaporthe oryzae homeostasis blast disease ER stress

Information
- Symbol: OsHLP1
- MSU: LOC_Os11g05800
- RAPdb: Os11g0156600
Publication
- A rice protein modulates endoplasmic reticulum homeostasis and coordinates with a transcription factor to initiate blast disease resistance., 2021, Cell Rep.
Genbank accession number
Key message
- OsHLP1 interacts with the NAC (NAM, ATAF, and CUC) transcription factor OsNTL6 at the ER
- Overexpression of OsHLP1 significantly enhances blast disease resistance but impairs ER morphology in rice (Oryza sativa), resulting in enhanced sensitivity to ER stress
- OsHLP1 suppresses OsNTL6 protein accumulation, whereas OsNTL6 counteracts OsHLP1 by alleviating sensitivity to ER stress and decreasing disease resistance in OsHLP1 overexpression plants
- These findings unravel a mechanism whereby OsHLP1 promotes disease resistance by compromising ER homeostasis when plants are infected by pathogens
- Here we find that transcription of an HVA22 family gene, OsHLP1 (HVA22-like protein 1), is induced by Magnaporthe oryzae infection
Connection

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