- Information
- Symbol: Pikp-2
- MSU: LOC_Os11g46210
- RAPdb: Os11g0689100
- Publication
- The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes, 2011, Theor Appl Genet.
- Characterization of rice blast resistance genes in the Pik cluster and fine mapping of the Pik-p locus, 2009, Phytopathology.
- The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation, 2020, PLoS One.
- Genbank accession number
- Key message
- The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes
- Further, expression of individual Pikp-1 or Pikp-2 domains did not result in cell death
- Mutations in the conserved P-loop and MHD sequence motifs in both Pikp-1 and Pikp-2 prevented cell death activation, demonstrating that these motifs are required for the function of the two partner NLRs
- Connection
- Pikp-1, Pikp-2, The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes, Both Pikp-1 (KP3) and Pikp-2 (KP4) encode coiled-coil NBS-LRR proteins and share, respectively, 95 and 99% peptide identity with the two alleles, Pikm1-TS and Pikm2-TS
- Pikp-1, Pikp-2, The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes, The Pikp-1 and Pikp-2 sequences share only limited homology
- Pikp-1, Pikp-2, The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes, Both Pikp-1 and Pikp-2 were constitutively expressed in cv
- Pikp-1, Pikp-2, The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation, We found that any domain truncation, in either Pikp-1 or Pikp-2, prevented cell death in the presence of AVR-PikD, revealing that all domains are required for activity
- Pikp-1, Pikp-2, The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation, Further, expression of individual Pikp-1 or Pikp-2 domains did not result in cell death
- Pikp-1, Pikp-2, The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation, Mutations in the conserved P-loop and MHD sequence motifs in both Pikp-1 and Pikp-2 prevented cell death activation, demonstrating that these motifs are required for the function of the two partner NLRs
- Pikp-1, Pikp-2, The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation, Finally, we showed that Pikp-1 and Pikp-2 associate to form homo- and hetero-complexes in planta in the absence of AVR-PikD; on co-expression the effector binds to Pikp-1 generating a tri-partite complex
- Pikp-1, Pikp-2, The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation, Taken together, we provide evidence that Pikp-1 and Pikp-2 form a fine-tuned system that is activated by AVR-PikD via receptor cooperation rather than negative regulation
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