MIR

2015-01-20 | Categories genes  | Tags growth  iron  mitochondria  root  homeostasis  shoot 

• Information
  • Symbol: MIR
  • MSU: LOC_Os12g18410
  • RAPdb: Os12g0282000
• Publication
  • Rice-specific mitochondrial iron-regulated gene MIR plays an important role in iron homeostasis, 2009, Mol Plant.
• Genbank accession number
  • AK103636
• Key message
  • Growth in the MIR T-DNA knockout rice mutant (mir) was significantly impaired compared to wild-type (WT) plants when grown under Fe-deficient or -sufficient conditions
  • We cloned and characterized a mitochondrial iron-regulated (MIR) gene in rice involved in Fe homeostasis
  • Rice-specific mitochondrial iron-regulated gene (MIR) plays an important role in iron homeostasis
  • MIR, when expressed in tobacco BY-2 cells, was localized to the mitochondria
  • These results clearly suggest that MIR is a rice-specific mitochondrial protein, recently evolved, and plays a significant role in Fe homeostasis
  • MIR transcripts were greatly increased in response to Fe deficiency in roots and shoot tissue
  • Furthermore, mir plants accumulated more than twice the amount of Fe in shoot and root tissue compared to WT plants when grown under either Fe-sufficient or -deficient conditions
  • Despite the high accumulation of Fe in roots and shoots, mir plants triggered the expression of Fe-deficiency-inducible genes, indicating that mir may not be able to utilize Fe for physiological functions
• Connection

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