SDEL1,OsMSRFP

• Symbol: SDEL1,OsMSRFP
• MSU: LOC_Os12g35320
• RAPdb: Os12g0538500

• Two RING-finger ubiquitin E3 ligases regulate the degradation of SPX4, the internal phosphate sensor, for phosphate homeostasis and signaling in rice., 2019, Mol Plant.
• The transcription factor OsMYBc and an E3 ligase regulate expression of a K+ transporter during salt stress., 2022, Plant Physiol.

Genbank accession number

• Consistent with this biochemical function of SDEL1 and SDEL2, enhancing the expression of SDEL1 and SDEL2 results in Pi over-accumulation and induces Pi-starvation signaling even under Pi-sufficient conditions
• Therefore SDEL1 and SDEL2 facilitate the degradation of SPX4 to modulate PHR2 activity and regulate Pi-homeostasis and Pi-signaling in response to external Pi availability in rice
• OsMSRFP attenuated OsMYBc-mediated OsHKT1;1 expression, and knockout of OsMSRFP led to rice salt tolerance

• OsHKT1;1~OsHKT4, SDEL1~OsMSRFP, The transcription factor OsMYBc and an E3 ligase regulate expression of a K+ transporter during salt stress., OsMSRFP attenuated OsMYBc-mediated OsHKT1;1 expression, and knockout of OsMSRFP led to rice salt tolerance
• OsROC1~OsMYBc, SDEL1~OsMSRFP, The transcription factor OsMYBc and an E3 ligase regulate expression of a K+ transporter during salt stress., A yeast two-hybrid screen using the OsMYBc N terminus as bait identified a rice MYBc stress-related RING finger protein (OsMSRFP)
• OsROC1~OsMYBc, SDEL1~OsMSRFP, The transcription factor OsMYBc and an E3 ligase regulate expression of a K+ transporter during salt stress., OsMSRFP is an active E3 ligase that ubiquitinated OsMYBc in vitro and mediated 26S proteasome-mediated degradation of OsMYBc under semi-in vitro and in vivo conditions