- Information
    
- Symbol: OFP3
 - MSU: None
 - RAPdb: None
 
 - Publication
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Genbank accession number
 - Key message
    
- While knockout of OFP3 promoted rice seedling growth, overexpression of OFP3 led to strong BR insensitivity, which resulted in reduced plant height, leaf angle, and grain size
 - GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice.
 - Here, we identified OFP3 (OVATE FAMILY PROTEIN 3) as an interactor of both GSK2 and DLT by yeast two-hybrid screening and demonstrated that OFP3 plays a distinctly negative role in BR responses
 - Moreover, treatment with either BR or bikinin, a GSK3-like kinase inhibitor, induced OFP3 depletion, whereas GSK2 or brassinazole, a BR synthesis inhibitor, promoted OFP3 accumulation
 
 - Connection
    
- D6~OSH15~Oskn3~RLB, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Furthermore, OFP3 exhibited transcription repressor activity and was able to interact with itself as well as additional BR-related components, including OFP1, OSH1, OSH15, OsBZR1, and GF14c
 - DLT~OsGRAS-32~D62~GS6~SMOS2, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Here, we identified OFP3 (OVATE FAMILY PROTEIN 3) as an interactor of both GSK2 and DLT by yeast two-hybrid screening and demonstrated that OFP3 plays a distinctly negative role in BR responses
 - GF14c~OsGF14C, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Furthermore, OFP3 exhibited transcription repressor activity and was able to interact with itself as well as additional BR-related components, including OFP1, OSH1, OSH15, OsBZR1, and GF14c
 - GSK2~OsGSK2~OsSK22, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice.
 - GSK2~OsGSK2~OsSK22, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Here, we identified OFP3 (OVATE FAMILY PROTEIN 3) as an interactor of both GSK2 and DLT by yeast two-hybrid screening and demonstrated that OFP3 plays a distinctly negative role in BR responses
 - GSK2~OsGSK2~OsSK22, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Moreover, treatment with either BR or bikinin, a GSK3-like kinase inhibitor, induced OFP3 depletion, whereas GSK2 or brassinazole, a BR synthesis inhibitor, promoted OFP3 accumulation
 - GSK2~OsGSK2~OsSK22, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Importantly, GSK2 can phosphorylate OFP3 and enhance these interactions
 - GSK2~OsGSK2~OsSK22, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., We propose that OFP3, as a suppressor of both BR synthesis and signaling but stabilized by GSK2, incorporates into a transcription factor complex to facilitate BR signaling control, which is critical for the proper development of various tissues
 - OFP1, OFP3, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Furthermore, OFP3 exhibited transcription repressor activity and was able to interact with itself as well as additional BR-related components, including OFP1, OSH1, OSH15, OsBZR1, and GF14c
 - OFP3, OsBZR1~BZR1, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Furthermore, OFP3 exhibited transcription repressor activity and was able to interact with itself as well as additional BR-related components, including OFP1, OSH1, OSH15, OsBZR1, and GF14c
 - OFP3, OSH1~Oskn1, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Furthermore, OFP3 exhibited transcription repressor activity and was able to interact with itself as well as additional BR-related components, including OFP1, OSH1, OSH15, OsBZR1, and GF14c
 
 
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