OsNTL3

• Symbol: OsNTL3
• MSU: LOC_Os01g15640
• RAPdb: Os01g0261200

• A membrane-associated NAC transcription factor OsNTL3 is involved in thermotolerance in rice., 2019, Plant Biotechnol J.

Genbank accession number

• A membrane-associated NAC transcription factor OsNTL3 is involved in thermotolerance in rice.
• OsNTL3 encodes a NAC transcription factor with a predicted C-terminal transmembrane domain
• Loss-of-function mutation of OsNTL3 confers heat sensitivity while inducible expression of the truncated form of OsNTL3 without the transmembrane domain increases heat tolerance in rice seedlings
• In the current study, we discovered that OsNTL3 is required for heat stress tolerance in rice
• Interestingly, OsNTL3 directly binds to OsbZIP74 promoter and regulates its expression in response to heat stress
• In turn, up-regulation of OsNTL3 by heat stress is dependent on OsbZIP74
• Thus, our work reveals the important role of OsNTL3 in thermotolerance, and a regulatory circuit mediated by OsbZIP74 and OsNTL3 in communications among ER, plasma membrane and nucleus under heat stress conditions
• RNA-Seq analysis revealed that OsNTL3 regulates the expression of genes involved in ER protein folding and other processes

• OsbZIP50~OsbZIP74, OsNTL3, A membrane-associated NAC transcription factor OsNTL3 is involved in thermotolerance in rice., Interestingly, OsNTL3 directly binds to OsbZIP74 promoter and regulates its expression in response to heat stress
• OsbZIP50~OsbZIP74, OsNTL3, A membrane-associated NAC transcription factor OsNTL3 is involved in thermotolerance in rice., In turn, up-regulation of OsNTL3 by heat stress is dependent on OsbZIP74
• OsbZIP50~OsbZIP74, OsNTL3, A membrane-associated NAC transcription factor OsNTL3 is involved in thermotolerance in rice., Thus, our work reveals the important role of OsNTL3 in thermotolerance, and a regulatory circuit mediated by OsbZIP74 and OsNTL3 in communications among ER, plasma membrane and nucleus under heat stress conditions