MPR25

2015-01-20 | Categories genes  | Tags mitochondria  chloroplast  growth 

• Information
  • Symbol: MPR25
  • MSU: LOC_Os04g51350
  • RAPdb: Os04g0602600
• Publication
  • Rice MPR25 encodes a pentatricopeptide repeat protein and is essential for RNA editing of nad5 transcripts in mitochondria, 2012, Plant J.
  • AEF1/MPR25 is implicated in RNA editing of plastid atpF and mitochondrial nad5 and also promotes atpF splicing in Arabidopsis and rice., 2015, Plant J.
• Genbank accession number
  • AK120600
• Key message
  • In this study, we investigated the molecular function in rice of the mitochondrial PPR-encoding gene MITOCHONDRIAL PPR25 (MPR25), which belongs to the E subgroup of the PPR family
  • FLAG-tagged MPR25 accumulated in mitochondria but not in chloroplasts
  • Direct sequencing revealed that the mpr25 mutant fails to edit a C-U RNA editing site at nucleotide 1580 of nad5, which encodes a subunit of complex I (NADH dehydrogenase) of the respiratory chain in mitochondria
  • The mpr25 mutant may therefore provide new information on the coordinated interaction between mitochondria and chloroplasts
  • Rice MPR25 encodes a pentatricopeptide repeat protein and is essential for RNA editing of nad5 transcripts in mitochondria
  • A Tos17 knockout mutant of MPR25 exhibited growth retardation and pale-green leaves with reduced chlorophyll content during the early stages of plant development
  • We also show that splicing of chloroplast atpF transcripts is affected in the rice mpr25 mutant
• Connection

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