OsBZR1,BZR1

• Symbol: OsBZR1,BZR1
• MSU: LOC_Os07g39220
• RAPdb: Os07g0580500

• DWARF AND LOW-TILLERING, a new member of the GRAS family, plays positive roles in brassinosteroid signaling in rice, 2009, The Plant Journal.
• Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, 2012, PLoS Genet.
• Functions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice, 2007, Proc Natl Acad Sci U S A.
• OsmiR396d miRNA affects gibberellin and brassinosteroid signaling to regulate plant architecture., 2017, Plant Physiol.
• Strigolactones and brassinosteroids antagonistically regulate the stability of D53-OsBZR1 complex to determine FC1 expression in rice tillering., 2019, Mol Plant.
• OrMKK3 Influences Morphology and Grain Size in Rice, 2021, J Plant Biol.
• Decreased grain size1, a C3HC4-type RING protein, influences grain size in rice Oryza sativa L., 2021, Plant Mol Biol.
• The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression, 2021, Plant J.
• BZR1 Regulates Brassinosteroid-Mediated Activation of AMT1;2 in Rice, 2021, Front Plant Sci ..
• qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, 2021, Plant Physiol.
• GLUTAMATE RECEPTOR-like gene OsGLR3.4 is required for plant growth and systemic wound signaling in rice Oryza sativa., 2021, New Phytol.
• The Histone Deacetylase 1/ GSK3/SHAGGY-Like Kinase 2/ BRASSINAZOLE RESISTANT 1 Module Controls Lateral Root Formation in Rice., 2022, Plant Physiol.
• Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., 2022, Plant Cell Environ.
• Mutation of phytochrome B promotes resistance to sheath blight and saline-alkaline stress via increasing ammonium uptake in rice., 2022, Plant J.

Genbank accession number

• These results demonstrate a conserved function of OsBZR1 and an important role of 14-3-3 proteins in brassinosteroid signal transduction in rice
• Functions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice
• To understand the downstream BR signaling mechanism in rice, we studied the function of OsBZR1 using reverse genetic approaches and identified OsBZR1-interacting proteins
• Suppressing OsBZR1 expression by RNAi resulted in dwarfism, erect leaves, reduced BR sensitivity, and altered BR-responsive gene expression in transgenic rice plants, demonstrating an essential role of OsBZR1 in BR responses in rice
• Finally, consistent with the fact that DLT is also negatively feedback-regulated by BR treatment, a gel mobility shift assay showed that OsBZR1 can bind to the DLT promoter through the BR-response element
• We reported that DGS1 plays a positive role in regulating grain size in rice and was regulated by OsBZR1
• OsBZR1 (BRASSINAZOLE-RESISTANT1), a core transcription activator of BR signaling, also plays a positive role in grain size
• The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression
• We further show that GRAIN NUMBER, PLANT HEIGHT, and HEADING DATE 7 (Ghd7), a central regulator of growth, development, and the stress response, is a direct target of OsBZR1
• We also show that HDA703 is a direct target of BRASSINAZOLE-RESISTANT1 (OsBZR1), a primary regulator of rice BR signaling, and HDA703 interacts with OsBZR1 in rice
• Together, our study suggests that HDA703, a histone H4 deacetylase, interacts with OsBZR1 to regulate rice BR signaling, growth, and heading date through epigenetic regulation of Ghd7
• Moreover, cellular ammonium contents, 15NH4 + uptake, and the regulatory effect of methyl-ammonium on root growth are strongly dependent on the levels of BZR1
• qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling
• Genetic and molecular analyses indicated that OsGF14b functions as a negative regulator in BR signaling and represses the transcriptional activation activity of OsBZR1
• OsGSK2 deacetylation attenuated the interaction between OsGSK2 and BRASSINAZOLE RESISTANT 1 (OsBZR1), leading to accumulation of OsBZR1
• Although BZR1 is known to regulate brassinosteroid (BR) signalling, the observation that BR signalling negatively regulated resistance to ShB indicated an independent role for BZR1 in controlling rice resistance
• Plants overexpressing PIL15 were more susceptible to ShB in contrast to bzr1-D-overexpressing plants compared with the wild-type, suggesting that PhyB may inhibit BZR1 to negatively regulate rice resistance to ShB
• It was also found that the BZR1 ligand NAC028 positively regulated resistance to ShB

• DLT~OsGRAS-32~D62~GS6~SMOS2, OsBZR1~BZR1, DWARF AND LOW-TILLERING, a new member of the GRAS family, plays positive roles in brassinosteroid signaling in rice, Finally, consistent with the fact that DLT is also negatively feedback-regulated by BR treatment, a gel mobility shift assay showed that OsBZR1 can bind to the DLT promoter through the BR-response element
• ILI1, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, LIC directly regulated target genes such as INCREASED LEAF INCLINATION 1 (ILI1) to oppose the action of BZR1
• ILI1, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, Repression of LIC in ILI1 transcription in protoplasts was partially rescued by BZR1
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, Here, we demonstrate that Oryza sativa LEAF and TILLER ANGLE INCREASED CONTROLLER (LIC) acts as an antagonistic transcription factor of BRASSINAZOLE-RESISTANT 1 (BZR1) to attenuate the BR signaling pathway
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, The gain-of-function mutant lic-1 and LIC-overexpressing lines showed erect leaves, similar to BZR1-depleted lines, which indicates the opposite roles of LIC and BZR1 in regulating leaf bending
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, For negative feedback, LIC bound to the core element CTCGC in the BZR1 promoter on gel-shift and chromatin immunoprecipitation assay and repressed its transcription on transient transformation assay
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, LIC directly regulated target genes such as INCREASED LEAF INCLINATION 1 (ILI1) to oppose the action of BZR1
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, Repression of LIC in ILI1 transcription in protoplasts was partially rescued by BZR1
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, Phenotypic analysis of the crossed lines depleted in both LIC and BZR1 suggested that BZR1 functionally depends on LIC
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, Molecular and physiology assays revealed that LIC plays a dominant role at high BR levels, whereas BZR1 is dominant at low levels
• LIC~OsLIC1~OsLIC~OsFLA6, OsBZR1~BZR1, Dynamics of brassinosteroid response modulated by negative regulator LIC in rice, Thus, LIC regulates rice leaf bending as an antagonistic transcription factor of BZR1
• CSA, OsBZR1~BZR1, Brassinosteroids Promote Development of Rice Pollen Grains and Seeds by Triggering Expression of CSA, a MYB Domain Protein., Mechanically, OsBZR1 directly promotes CSA expression and CSA directly triggers expression of sugar partitioning and metabolic genes during pollen and seed development
• OsBZR1~BZR1, OsDof12~OsCDF1, Overexpression of OsDof12 affects plant architecture in rice Oryza sativa L.., Of note, in WT plants the expression of OsDof12 was found up-regulated by BR treatment while in OsDof12 overexpression plants two positive BR signaling regulators, OsBRI1 and OsBZR1, were significantly down-regulated, indicating that OsDof12 may act as a negative BR regulator in rice
• OsBZR1~BZR1, OsPRA2, A Small G Protein as a Novel Component of the Rice Brassinosteroid Signal Transduction., Mechanistic study uncovered that OsPRA2 inhibited the dephosphorylation of, and thus inactivated the transcription factor BRASSINAZOLE-RESISTANT 1 (OsBZR1)
• OsBZR1~BZR1, OsPRA2, A Small G Protein as a Novel Component of the Rice Brassinosteroid Signal Transduction., Together, these results revealed a possible working mechanism of OsPRA2 as a novel negative regulator on OsBRI1 and OsBZR1 in the BR signaling pathway in rice, and further extended the knowledge about the regulatory mechanism of rice BR signaling
• GW5~qSW5, OsBZR1~BZR1, GW5 acts in the brassinosteroid signalling pathway to regulate grain width and weight in rice., GW5 protein is localized to the plasma membrane and can physically interact with and repress the kinase activity of rice GSK2 (glycogen synthase kinase 2), a homologue of Arabidopsis BIN2 (BRASSINOSTEROID INSENSITIVE2) kinase, resulting in accumulation of unphosphorylated OsBZR1 (Oryza sativa BRASSINAZOLE RESISTANT1) and DLT (DWARF AND LOW-TILLERING) proteins in the nucleus to mediate brassinosteroid (BR)-responsive gene expression and growth responses (including grain width and weight)
• OsBZR1~BZR1, OsPRA2, OsPRA2 fine-tunes rice brassinosteroid receptor., Recently we have reported that a rice small G protein, OsPRA2, bound to the BR receptor OsBRI1 at the plasma membrane (PM) and inhibited its kinase activity and its interaction with the co-receptor OsBAK1, leading to a lower sensitivity to BR treatment and dephosphorylation of OsBZR1
• OFP1, OsBZR1~BZR1, Brassinosteroids Regulate OFP1, a DLT Interacting Protein, to Modulate Plant Architecture and Grain Morphology in Rice., In addition, we found OFP1 was greatly induced by BR treatment, and OsBZR1, the critical transcription factor of BR signaling, was physically associated with the OFP1 promoter
• FZP~BFL1~SGDP7~PAA7, OsBZR1~BZR1, Duplication of an upstream silencer of FZP increases grain yield in rice., The transcription repressor OsBZR1 binds the CGTG motifs in CNV-18bp and thereby represses FZP expression, indicating that CNV-18bp is the upstream silencer of FZP
• OsBZR1~BZR1, OsPUB24, OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response., OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response.
• OsBZR1~BZR1, OsPUB24, OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response., Here, we report that a rice U-box E3 ubiquitin (Ub) ligase OsPUB24 acts as a negative regulator in the BR signaling pathway via 26S proteasome-dependent degradation of OsBZR1
• OsBZR1~BZR1, OsPUB24, OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response., OsPUB24 ubiquitinated OsBZR1, resulting in the proteasomal degradation of OsBZR1
• OsBZR1~BZR1, OsPUB24, OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response., Our findings suggest that OsPUB24 participates in OsBZR1 turnover and the regulatory networks of OsPUB24, OsSK22, and OsBZR1 are crucial for fine-tuning the BR response in rice
• GSK2~OsGSK2~OsSK22, OsBZR1~BZR1, OsBZR1 turnover mediated by OsSK22-regulated U-box E3 ligase OsPUB24 in rice BR response., Our findings suggest that OsPUB24 participates in OsBZR1 turnover and the regulatory networks of OsPUB24, OsSK22, and OsBZR1 are crucial for fine-tuning the BR response in rice
• OsBZR1~BZR1, OsGSK3, Rice qGL3/OsPPKL1 Functions with the GSK3/SHAGGY-Like Kinase OsGSK3 to Modulate Brassinosteroid Signaling., Knocking-out of OsGSK3 enhances BR signaling and induces nuclear localization of Oryza sativa BRASSINAZOLE RESISTANT1 (OsBZR1)
• OsBZR1~BZR1, OsGSK3, Rice qGL3/OsPPKL1 Functions with the GSK3/SHAGGY-Like Kinase OsGSK3 to Modulate Brassinosteroid Signaling., These results demonstrate that qGL3 suppresses BR signaling by regulating the phosphorylation and stability of OsGSK3, which modulates OsBZR1 phosphorylation and subcellular distribution
• D53, OsBZR1~BZR1, Strigolactones and brassinosteroids antagonistically regulate the stability of D53-OsBZR1 complex to determine FC1 expression in rice tillering., Further experiments demonstrate that D53 interacts with OsBZR1 to inhibit FC1 expression, the local inhibitor for tillering, which depends on the direct DNA-binding by OsBZR1 to recruit D53 to FC1 promoter in rice buds
• OFP3, OsBZR1~BZR1, GSK2 Stabilizes OFP3 to Suppress Brassinosteroid Responses in Rice., Furthermore, OFP3 exhibited transcription repressor activity and was able to interact with itself as well as additional BR-related components, including OFP1, OSH1, OSH15, OsBZR1, and GF14c
• OsBZR1~BZR1, OsMED25, Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate Brassinosteroid signaling and plant architecture in rice., Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate Brassinosteroid signaling and plant architecture in rice.
• OsBZR1~BZR1, OsMED25, Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate Brassinosteroid signaling and plant architecture in rice., Further biochemical analysis showed that OsMED25 interacts with OsBZR1 in vivo, and OsMED25 is enriched on the promoter of OsBZR1 target genes
• OsBZR1~BZR1, OsMED25, Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate Brassinosteroid signaling and plant architecture in rice., RNA sequencing analysis indicated that OsMED25 affects the expression of approximately 45% of OsBZR1-regulated genes and mainly functions as a co-repressor of OsBZR1
• OsBZR1~BZR1, OsMED25, Oryza sativa mediator subunit OsMED25 interacts with OsBZR1 to regulate Brassinosteroid signaling and plant architecture in rice., Together, these findings revealed that OsMED25 regulates rice BR signaling by interacting with OsBZR1 and modulating the expression of OsBZR1 target genes, thus expanding our understanding of the roles of mediators in plant hormone signaling
• Ghd7, OsBZR1~BZR1, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression
• Ghd7, OsBZR1~BZR1, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression, We further show that GRAIN NUMBER, PLANT HEIGHT, and HEADING DATE 7 (Ghd7), a central regulator of growth, development, and the stress response, is a direct target of OsBZR1
• Ghd7, OsBZR1~BZR1, The histone deacetylase HDA703 interacts with OsBZR1 to regulate rice brassinosteroid signaling, growth and heading date through repression of Ghd7 expression, Together, our study suggests that HDA703, a histone H4 deacetylase, interacts with OsBZR1 to regulate rice BR signaling, growth, and heading date through epigenetic regulation of Ghd7
• GF14b~OsGF14b, OsBZR1~BZR1, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling
• GF14b~OsGF14b, OsBZR1~BZR1, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, qGL3 promoted the phosphorylation of OsGF14b and induced the interaction intensity between OsGF14b and OsBZR1
• GF14b~OsGF14b, OsBZR1~BZR1, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, In addition, phosphorylation of OsGF14b played an important role in regulating nucleocytoplasmic shuttling of OsBZR1
• GF14b~OsGF14b, OsBZR1~BZR1, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, Genetic and molecular analyses indicated that OsGF14b functions as a negative regulator in BR signaling and represses the transcriptional activation activity of OsBZR1
• GF14b~OsGF14b, OsBZR1~BZR1, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, Collectively, these results demonstrate that qGL3 induces the phosphorylation of OsGF14b, which modulates nucleocytoplasmic shuttling and transcriptional activation activity of OsBZR1, to eventually negatively regulate BR signaling and grain length in rice
• GL3.1~qGL3-1~qGL3~OsPPKL1, OsBZR1~BZR1, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, qGL3 promoted the phosphorylation of OsGF14b and induced the interaction intensity between OsGF14b and OsBZR1
• GL3.1~qGL3-1~qGL3~OsPPKL1, OsBZR1~BZR1, qGL3/OsPPKL1 Induces Phosphorylation of 14-3-3 OsGF14b to Inhibit OsBZR1 Function in Brassinosteroid Signaling, Collectively, these results demonstrate that qGL3 induces the phosphorylation of OsGF14b, which modulates nucleocytoplasmic shuttling and transcriptional activation activity of OsBZR1, to eventually negatively regulate BR signaling and grain length in rice
• OsBZR1~BZR1, OsHDAC1, The Histone Deacetylase 1/ GSK3/SHAGGY-Like Kinase 2/ BRASSINAZOLE RESISTANT 1 Module Controls Lateral Root Formation in Rice., Taken together, the results indicate that OsHDAC1 regulates LR formation in rice by deactivating OsGSK2, thereby preventing degradation of OsBZR1, a positive regulator of LR primordia formation
• GSK2~OsGSK2~OsSK22, OsBZR1~BZR1, The Histone Deacetylase 1/ GSK3/SHAGGY-Like Kinase 2/ BRASSINAZOLE RESISTANT 1 Module Controls Lateral Root Formation in Rice., OsGSK2 deacetylation attenuated the interaction between OsGSK2 and BRASSINAZOLE RESISTANT 1 (OsBZR1), leading to accumulation of OsBZR1
• GSK2~OsGSK2~OsSK22, OsBZR1~BZR1, The Histone Deacetylase 1/ GSK3/SHAGGY-Like Kinase 2/ BRASSINAZOLE RESISTANT 1 Module Controls Lateral Root Formation in Rice., Taken together, the results indicate that OsHDAC1 regulates LR formation in rice by deactivating OsGSK2, thereby preventing degradation of OsBZR1, a positive regulator of LR primordia formation
• OsBZR1~BZR1, SRS3~OsKINESIN-13A~BHS1, The kinesin-13 protein BR HYPERSENSITIVE 1 is a negative brassinosteroid signaling component regulating rice growth and development., Furthermore, we found that the BR-induced degradation of BHS1 was attenuated in Osbri1 and Osbak1 mutants, but not in Osbzr1 and Oslic mutants
• OsBZR1~BZR1, OsPUB43, CRISPR-Cas9 Mediated Mutation in OsPUB43 Improves Grain Length and Weight in Rice by Promoting Cell Proliferation in Spikelet Hull., Furthermore, the transient transcriptional activity assay shows that OsBZR1 can activate the expression of OsPUB43
• OsBZR1~BZR1, OsCPL3, OsCPL3 is involved in brassinosteroid signaling by regulating OsGSK2 stability., Loss of OsCPL3 function resulted in higher OsGSK2 abundance and lower OsBZR1 levels, leading to decreased BR responsiveness and alterations in plant morphology including semi-dwarfism, leaf erectness and grain size, which are of fundamental importance to crop productivity
• OsBZR1~BZR1, OsCPL3, OsCPL3 is involved in brassinosteroid signaling by regulating OsGSK2 stability., OsCPL3 localized to the nucleus, where it dephosphorylated OsGSK2 at the Ser-222 and Thr-284 residues to modulate its protein turnover and kinase activity, in turn affecting the degradation of BRASSINAZOLE-RESISTANT 1 (BZR1) and BR signaling
• HDA703, OsBZR1~BZR1, Ammonium protects rice against rice stripe virus by activating HDA703/OsBZR1-mediated BR signaling., HDA703, a histone deacetylase and OsBZR1, a transcription factor, are two positive regulator of BR signaling and interact with each other
• HDA703, OsBZR1~BZR1, Ammonium protects rice against rice stripe virus by activating HDA703/OsBZR1-mediated BR signaling., We also show that in contrast to NO(3)(-), NH(4)(+) does not affect BR biosynthesis but promotes BR signaling by upregulating the expression of HDA703 and promoting the accumulation of OsBZR1 in rice shoots
• NAC028, OsBZR1~BZR1, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., It was also found that the BZR1 ligand NAC028 positively regulated resistance to ShB
• NAC028, OsBZR1~BZR1, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., Yeast-one hybrid, ChIP, and transactivation assays demonstrated that BZR1 and NAC028 activate CAD8B directly
• CAD8B, OsBZR1~BZR1, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., Yeast-one hybrid, ChIP, and transactivation assays demonstrated that BZR1 and NAC028 activate CAD8B directly
• OsBZR1~BZR1, PHYB~OsphyB, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., Further analysis showed that PhyB interacts with phytochrome-interacting factor-like 15 (PIL15), brassinazole resistant 1 (BZR1), and vascular plant one-zinc-finger 2 (VOZ2)
• OsBZR1~BZR1, PHYB~OsphyB, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., Plants overexpressing PIL15 were more susceptible to ShB in contrast to bzr1-D-overexpressing plants compared with the wild-type, suggesting that PhyB may inhibit BZR1 to negatively regulate rice resistance to ShB
• OsBZR1~BZR1, SMOS1~SHB~RLA1~NGR5, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., Plants overexpressing PIL15 were more susceptible to ShB in contrast to bzr1-D-overexpressing plants compared with the wild-type, suggesting that PhyB may inhibit BZR1 to negatively regulate rice resistance to ShB
• OsBZR1~BZR1, SMOS1~SHB~RLA1~NGR5, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., Although BZR1 is known to regulate brassinosteroid (BR) signalling, the observation that BR signalling negatively regulated resistance to ShB indicated an independent role for BZR1 in controlling rice resistance
• OsBZR1~BZR1, SMOS1~SHB~RLA1~NGR5, Red-light receptor phytochrome B inhibits BZR1-NAC028-CAD8B signaling to negatively regulate rice resistance to sheath blight., It was also found that the BZR1 ligand NAC028 positively regulated resistance to ShB
• OsBSK1-1, OsBZR1~BZR1, BRASSINOSTEROID-SIGNALING KINASE1-1, a positive regulator of brassinosteroid signalling, modulates plant architecture and grain size in rice., Moreover, we showed that OsBSK1-1 can be phosphorylated by OsBRI1 and can inhibit OsGSK2-mediated phosphorylation of BRASSINOSTEROID RESISTANT1 (OsBZR1)
• D61~OsBRI1~OsBRKq1~HFR131, OsBZR1~BZR1, BRASSINOSTEROID-SIGNALING KINASE1-1, a positive regulator of brassinosteroid signalling, modulates plant architecture and grain size in rice., Moreover, we showed that OsBSK1-1 can be phosphorylated by OsBRI1 and can inhibit OsGSK2-mediated phosphorylation of BRASSINOSTEROID RESISTANT1 (OsBZR1)
• NIGT1, OsBZR1~BZR1, NIGT1 represses plant growth and mitigates phosphate starvation signaling to balance the growth response tradeoff in rice., We further demonstrate that NIGT1 constrains shoot growth by repressing the expression of growth-related regulatory genes, including brassinolide signal transduction master regulator BZR1, cell division regulator CYCB1;1, and DNA replication regulator PSF3